脑诱发电位分析与功能定位

发布时间：2018-01-24 08:03

本文关键词： 脑电波事件相关电位独立成分分析部分定向相关性脑功能区域定位　出处：《天津大学》2012年硕士论文　论文类型：学位论文

【摘要】：大脑为中枢神经系统的最高级中枢，各皮质的功能复杂，不仅与躯体的各种感觉和运动有关，也与语言、文字等密切相关。因此在进行运动和语言活动时，脑部与运动和语言相关的区域会活化程度较高。此外在测量脑波的同时伴随着干扰波的产生，干扰波常使脑波的判读发生困难，因此在侦测脑波的过程中或事后的脑波处理中，必须尽可能地将干扰波滤除。本论文的目的既是开发能够去除脑波信号中各种干扰波和进行脑部功能区域定位的方法。以采集到的原始脑波信号为基础，探究基于盲源信号分离法的独立成分分析法中的两种方法消息量最大化Infomax和二阶盲辨识Sobi在去除脑波干扰中各自的优缺点，在此基础上将Infomax和Sobi方法进行结合，开发一套Two-stage脑波干扰去除系统，构造模拟数据对该系统进行测试，结果表明该系统能够很好得去除各种类型的脑波干扰且效果优于单独始终Infomax或Sobi。通过设计运动和语言脑波实验，对受测者进行脑波数据收案。构造一套脑部功能区域定位方法，将脑波事件相关电位ERP数据进行独立成分分析处理，提取其中的P300和N170成份，将得到的P300和N170成份做部分定向相关性PDC计算，得到脑部各个区域电极的信号流向情况，据此判断遇到特定刺激时该区域的活化程度，，从而助于进行脑部功能区域定位。
[Abstract]:The brain is the most advanced center of the central nervous system, the function of each cortex is complex, not only with the body of various senses and movements, but also with language, writing and other closely related. Therefore, in the exercise and language activities. Areas of the brain associated with movement and language are highly activated. In addition, the measurement of brain waves is accompanied by the production of interference waves, which often make it difficult to interpret brain waves. So in the process of detecting the brain wave or in the subsequent processing of the brain wave. The purpose of this paper is to develop a method to remove all kinds of interference waves and locate the functional regions of the brain. Based on the original brain signals collected. This paper explores the advantages and disadvantages of the two independent component analysis methods based on blind source signal separation (BSS), namely maximization of Infomax and second-order blind identification Sobi in the removal of brain wave interference. On this basis, the Infomax and Sobi methods are combined to develop a set of Two-stage brain wave interference removal system, and construct simulation data to test the system. The results show that the system can remove all kinds of brain wave interference and the effect is better than that of Infomax or Sobi alone. Through the design of exercise and language brainwave experiment, the subjects were collected brain wave data, and a set of brain functional region location method was constructed. The ERP data of brain wave event-related potentials were processed by independent component analysis. The P300 and N170 components were extracted, and the P300 and N170 components were calculated by partial directional correlation PDC, and the signal flow of the electrodes in various regions of the brain was obtained. Therefore, the activation of the region is determined when a specific stimulus is encountered, thus facilitating the localization of the functional regions of the brain.
【学位授予单位】：天津大学
【学位级别】：硕士
【学位授予年份】：2012
【分类号】：R338;TN911.7

【共引文献】