舰船多舱室爆炸致比格犬颅脑爆震伤模型建立及伤情分析

发布时间：2018-01-26 11:44

本文关键词： 爆震伤冲击波颅脑损伤船舶多舱室　出处：《第二军医大学学报》2017年01期 　论文类型：期刊论文

【摘要】：目的模拟舰船内爆炸后生物体的损伤情况,探索典型多舱室内爆炸后比格犬在爆炸冲击波、准静态压力作用下的颅脑损伤伤情特点。方法在等比例舰艇舱室模型中,使用0.65kg TNT裸药模拟舰船内爆炸,其中炸药安放舱为当舱,相邻舱室为邻舱。采用压力传感器测定冲击波物理参数。将24只比格犬随机分为2组,每组12只,分别置于当舱和邻舱中接受爆炸损伤。观察爆炸后犬存活情况、基本生命体征变化、神经功能评分以及颅脑大体和形态学改变。结果爆炸后舱室内会出现两次较大的反射冲击波,邻舱的冲击波压力峰值约为当舱的0.39倍。比格犬在爆炸后即刻死亡7只,24h内死亡4只,死亡率为45.83%(11/24),其中当舱动物死亡率为66.67%(8/12),邻舱动物死亡率为25.0%(3/12)。存活比格犬的基本生命体征和神经功能在爆后即刻有较大的改变,24h后基本恢复。即刻死亡的比格犬脑组织有明显的挫裂伤,爆炸后24h内死亡的比格犬脑组织可见脑出血和脑水肿;爆炸后存活比格犬的脑组织在光镜下也可见部分形态结构和神经元结构的异常,部分神经元出现核固缩深染、核溶解或核仁消失,细胞界限模糊。结论舰船多舱室爆炸后,当舱的冲击波压力明显高于邻舱,并且舱室内会出现二次反射冲击波,加重了对生物体的损伤;当舱比格犬的死亡率明显高于邻舱;比格犬在爆后即刻急性损伤最为严重,且脑组织有明显的病理变化。
[Abstract]:Objective to simulate the damage of organism in ship after the explosion, explore the typical multi compartment explosion in beagle dogs with shock wave, quasi craniocerebral injury injury characteristics under the action of static pressure. Methods in the proportion of ship cabin model, simulation of ship explosion in the use of 0.65kg TNT bare medicine, which is when the explosives placed cabin cabin to the cabin. The cabin adjacent pressure sensor for measuring shock wave physics parameters. 24 beagle dogs were randomly divided into 2 groups, 12 rats in each group were placed in the cabin when receiving the blast injury and the adjacent compartment. Observe the dogs survived after the explosion, the basic change of vital signs, nerve function score, brain and general morphological changes. Results the cabin interior explosion will appear two times larger reflected shock wave, adjacent cabin shock pressure peak is about 0.39 times when the cabin. Beagle in the explosion immediately after the death of 7, 24h died in 4, the death rate was 45.83 % (11/24), which when the animal mortality rate was 66.67% (8/12), adjacent cabin animal mortality rate was 25% (3/12). The survival of beagle dogs basic vital signs and neurological function in the burst immediately after a big change, the basic recovery after 24h. Brain tissues of beagle dogs died there was contusion, death 24h after the explosion of brain tissue in beagle dogs visible cerebral hemorrhage and cerebral edema; after the explosion of survival in beagle dogs brain tissue under light microscope is that part of the morphology and structure of neurons abnormal neurons karyopyknosis anachromasis, karyolysis or nucleolus disappeared, the cell boundaries blurred. Conclusion multi ship cabin after the explosion when the cabin, the shock wave pressure is higher than the next cabin and cabin will appear two times reflected shock wave, adding to the damage to living organisms; when the class of beagle dogs mortality was significantly higher than that of adjacent cabin; Beagle in the explosion immediately after acute injury is the most serious, There were obvious pathological changes in the brain tissue.

【作者单位】：第二军医大学海军临床医学院海军总医院神经外科;
【基金】：全军后勤科研重大项目(AHJ14J001)~~
【分类号】：R84;R-332
【正文快照】： [Acad J Sec Mil Med Univ,2017,38(1):106-111]颅脑战创伤是现代战争中导致舰员伤亡的重要因素。现代战争条件下的海战由于武器和环境的差异,既不同于既往海战,与现代陆战特点也有明显区别[1]。由于国内外均缺乏实战数据,对现代海战下的颅脑战创伤特点和机制等缺乏足够了解,

【相似文献】