肠道细菌Akkermansia muciniphila及其与宿主疾病的关系
发布时间:2018-03-18 14:56
本文选题:Akkermansia 切入点:muciniphila 出处:《卫生研究》2017年05期 论文类型:期刊论文
【摘要】:Akkermansia muciniphila(A.muciniphila)是肠道菌群的重要成员,于2004年首次从人类粪便样品中分离得到。A.muciniphila定植于肠道黏液层,其丰富度与肥胖、Ⅱ型糖尿病等代谢性疾病呈负相关。本文对A.muciniphila的基本特征、在肠道中的分布和变化情况、对宿主健康的影响及其与宿主代谢性疾病、免疫性疾病、肠道癌症、孤独症、酒精性肝病的关系等方面进行综述。
[Abstract]:Akkermansia muciniphila (A. muciniphila) is an important member of intestinal flora. In 2004, A. muciniphila was isolated from human fecal samples for the first time. The richness of A. muciniphila was negatively correlated with metabolic diseases such as obesity and type 鈪,
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