白细胞对偏振光的散射特性及散射特性与细胞结构的关系

发布时间：2018-03-24 15:26

本文选题：生物光学　切入点：细胞分析　出处：《中国激光》2017年10期

【摘要】：为了研究白细胞对偏振光的散射特性,运用几何光学近似理论修正偏振光传输的斯托克斯-穆勒矩阵元,基于偏心球模型数值模拟了两束偏振化方向互相垂直的偏振光入射时,不同形状、大小、折射率的无粒白细胞的散射光强空间分布以及散射特性与细胞结构的关系。不同条件下偏振光散射三维分布图像呈现不同的条纹特征,表明分布规律与细胞模型的形体参量和光学参量具有相关性。散射光强的差值、比值、差和比的分析结果表明,偏振光的后向散射反映了细胞内部更丰富的结构信息和光学信息。
[Abstract]:In order to study the scattering characteristics of polarized light by white blood cells, the Stokes-Muller matrix elements of polarized light transmission were modified by geometric optical approximation theory. The incident of polarized light with two polarized beams perpendicular to each other was numerically simulated based on the eccentric sphere model. The spatial distribution of scattering light intensity of granulocytes with different shapes, sizes and refractive index, and the relationship between scattering characteristics and cell structure. It is shown that the distribution law is related to the body parameters and optical parameters of the cell model, and the analysis results of the difference, ratio, sum ratio of scattered light intensity show that, The backscattering of polarized light reflects more abundant structural and optical information within the cell.
【作者单位】：江苏大学理学院;江苏大学机械工程学院;
【基金】：国家自然科学基金(11404145) 中国博士后科学基金(2014M550268) 江苏省博士后科研资助计划(1301148C)
【分类号】：O436;R329.27

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