食蟹猴自发性高血压及患病危险性的相关性研究

发布时间：2018-04-19 22:36

本文选题：食蟹猴 + 高血压　；参考：《中国比较医学杂志》2017年06期

【摘要】：目的建立各年龄段食蟹猴血压参考值。方法采用美国Beckman-CX4全自动生化分析仪和北京松下电工有限公司的腕式电子血压计,检测521只食蟹猴血压及血脂指标,对测定结果进行统计检验。结果经统计分析,不同年龄段的食蟹猴血压值差异显著,老年组食蟹猴血压值高于其它年龄组;老年组食蟹猴高血压的发病率高于其他年龄组,高血压组食蟹猴身体质量指数(body mass index,BMI)高于同年龄组血压正常的食蟹猴;老年组高脂血症食蟹猴高血压发病率高于其他年龄组。Logistic回归分析显示,年龄、BMI及高脂血症在预测高血压组的患病危险性的预测能力分别为血压正常组的1.435、1.218、2.337倍。结论初步建立不同年龄段食蟹猴的血压参考值。年龄、BMI、高脂血症为食蟹猴自发性高血压的危险因素,基础血压值测量为食蟹猴自发性高血压模型筛选及其相关研究提供了依据。
[Abstract]:Objective to establish the blood pressure reference value of crab monkey in different ages. Methods the blood pressure and blood lipid index of 521 crab monkeys were measured by Beckman-CX4 automatic biochemical analyzer and wrist type electronic sphygmomanometer of Beijing Matsushita Electrical Co., Ltd. Results by statistical analysis, there were significant differences in blood pressure between different age groups, the blood pressure in the elderly group was higher than that in the other age groups, the incidence of hypertension in the elderly group was higher than that in the other age groups, the incidence of hypertension in the elderly group was higher than that in the other age groups. The body mass index (BMI) in the hypertensive group was higher than that in the same age group, and the incidence of hypertension in the elderly group with hyperlipidemia was higher than that in the other age groups. The predictive ability of age BMI and hyperlipidemia in predicting the risk of hypertension was 1.435U 1.218v 2.337 times as high as that in normal blood pressure group, respectively. Conclusion the blood pressure reference value of crab monkey in different ages was preliminarily established. BMI, hyperlipidemia was the risk factor of spontaneous hypertension in crab-eating monkey. The basic blood pressure measurement provided the basis for screening spontaneous hypertension model of crab monkey and related research.
【作者单位】：昆明医科大学药学院暨省天然药物药理重点实验室;广西玮美生物科技有限公司;云南民族大学民族药资源化学国家民委-教育部重点实验室;
【基金】：国家“十二五”重大新药创制专项(编号:2011ZX09307-303) 广西科技计划项目(编号:桂科能14123006-7);广西科技计划项目(编号:桂科攻1347003-3)
【分类号】：R-332;R544.1

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