基于动态因果模型的视觉工作记忆任务脑效应网络研究

发布时间：2018-05-01 04:25

本文选题：工作记忆 + 动态因果模型　；参考：《航天医学与医学工程》2017年02期

【摘要】：目的从多通道脑电(electroencephalographys,EEGs)的效应连接角度,探究工作记忆的脑网络机制。方法收集15名健康志愿者的32通道脑电数据,通过源定位确定视觉工作记忆任务的激活脑区,在此基础上进行动态因果模型(DCM)分析,计算各连接的超越概率,构建工作记忆脑效应网络。结果双侧顶叶(PAR)到同侧背外侧前额叶(DLPFC)和双侧顶叶(PAR)到同侧额中线皮层(MFC)连接的超越概率大于其它连接。模型中正向连接簇的超越概率EP_forward大于反向连接簇的超越概率EP_backward和横向连接簇的超越概率EP_lateral(P0.01)。结论视觉工作记忆过程中,双侧顶叶与同侧背外侧前额叶、额中线皮层之间有信息交流,顶叶皮层的信息流向前额叶皮层。
[Abstract]:Objective to explore the brain network mechanism of working memory from the point of view of the effect connection of multichannel electroencephalography (EGs). Methods the 32 channel EEG data of 15 healthy volunteers were collected and the active brain regions of visual working memory tasks were determined by source location. The dynamic causality model (DCM) was used to calculate the transcendence probability of each connection. To construct the brain effect network of working memory. Results the transcendental probability between bilateral parietal cortex (parietal) to ipsilateral dorsolateral prefrontal fossa (DLPFC) and bilateral parietal parietal lobe (parietal) to ipsilateral midfrontal cortex was higher than that to other connections. In the model, the transcendental probability EP_forward of the forward connected cluster is greater than that of the reverse connected cluster's transcendence probability EP_backward and the transversely connected cluster's surpassing probability of EPlateral P0.01. Conclusion in the process of visual working memory, there is information exchange between bilateral parietal lobe and ipsilateral dorsolateral prefrontal lobe, and the information flow from parietal cortex to frontal cortex.
【作者单位】：天津医科大学生物医学工程与技术学院;
【基金】：国家自然科学基金(61471266)
【分类号】：R338

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