VEGFR2在血管新生与重塑中的调控作用

发布时间：2018-05-01 13:11

本文选题：血管新生 + VEGFR　；参考：《中国老年学杂志》2017年19期

【摘要】：正血管的新生与重塑作为血管发生,损伤与修复过程中的重要病理变化,在维护机体血管的结构与功能正常方面具有重要作用。尤其是在机体血管发生损伤情况下,血管的新生与重塑往往成为影响机体损伤发展及修复的重要影响因素。在机体损伤的急性期,相应损伤因子或炎症因子可通过促进损伤部位周围血管结构损伤或者重塑,从而改变局部的血液流变学特性,从而促进损伤组织炎症反应的发生,进而加重组织的损伤~([1]);而在恢复期,血管新生及新生血管结构重塑又是机体损
[Abstract]:As an important pathological change in the process of angiogenesis, injury and repair, the neovascularization and remodeling of positive blood vessels play an important role in maintaining the normal structure and function of blood vessels. Especially in the case of blood vessel injury, angiogenesis and remodeling often become an important factor to affect the development and repair of body injury. In the acute phase of body injury, the corresponding injury factors or inflammatory factors can change the local hemorheological characteristics by promoting the damage or remodeling of the vascular structure around the injured site, thus promoting the occurrence of inflammatory reaction in the injured tissue. In the recovery stage, angiogenesis and remodeling of the neovascularization structure are the damage to the body.
【作者单位】：上海中医药大学附属龙华医院消化科;上海中医药大学附属龙华医院脾胃病科;
【基金】：国家自然科学基金(No:81373616)
【分类号】：R363

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