等离子体射流联合刮治术治疗犬种植体周围炎的实验研究

发布时间：2018-05-17 20:15

本文选题：种植体周围炎 + 等离子体　；参考：《华中科技大学》2012年博士论文

【摘要】：目的：评价低温等离子体射流联合刮治术治疗犬种植体周围炎的临床、微生物、放射学和组织学成果。方法：拔除六只比格犬双侧下颌第一磨牙；三个月后种牙；三个月后埋线引导种植体周围炎形成,三个月后当种植体支持骨吸收40%时,除去引导线；采用树脂刮治器和0.2%氯己定葡萄糖酸盐治疗对照组,采用树脂刮治器、0.2%氯己定葡萄糖酸盐和等离子体喷流治疗实验组；在治疗前和治疗后三个月分别作龈沟出血指数、探诊深度、牙槽骨丧失深度和CT检查；在治疗后三个月作Micro CT和硬组织切磨片检查；在治疗前和治疗后1、2和3个月时,取微生物样本并作聚合酶链式反应(Polymerase chain reaction, PCR)分析。结果：在治疗后牙龈卟啉单胞菌(Porphyromonas gingivalis, Pg)和福赛拟杆菌(Bacteroides forsythus, Bf)的检出率有显著性下降(P0.05),实验组和对照组之间的差异有统计学意义(P0.05)；实验组的龈沟出血指数(sulcus bleeding index, SBI)和探诊深度(probing depth, PD)有显著性下降(P0.05),分别从4.42±0.58和4.77±1.45mm下降到1.21±0.58和2.52±0.7 mm,实验组和对照组之间的差异有统计学意义(P0.05)；实验组骨丧失深度(The distance from the shoulder of the implant to the bottom of the bony defect, DSB)有显著性下降(P0.05),从3.35±0.70mm下降到2.21±0.90 mm,实验组和对照组之间的差异有统计学意义(P0.05)。实验组新生骨大量形成,并且与种植体发生骨整合,对照组新生骨形成较少。结论：低温等离子体喷流联合刮治术治疗犬种植体周围炎取得了很好的治疗效果,改善了临床症状,减少了种植体周围的细菌,促进了种植体和牙槽骨的再结合。
[Abstract]:Objective: to evaluate the clinical, microbiological, radiological and histological results of low temperature plasma jet combined curettage in the treatment of canine periimplant inflammation. Methods: the first mandibular molars were extracted from six Beagle dogs; the first mandibular molars were planted after 3 months; the implant thread implantation led to the formation of periimplant inflammation three months later and the guiding line was removed when the implant support bone resorption was 40 months later. The control group was treated with resin curette and 0.2% chlorhexidine gluconate, and the experimental group was treated with 0.2% chlorhexidine gluconate and plasma jet. The depth of diagnosis, the depth of alveolar bone loss and CT were examined. Micro CT and hard tissue cutting and grinding were performed three months after treatment, and microorganism samples were collected and polymerase chain reaction (PCR) chain reaction, PCR) analysis was performed before treatment and 1 and 3 months after treatment. Results: after treatment, the detection rate of Porphyromonas gingivalis (Pgg) and Bacteroides forsythus (BfF) decreased significantly (P 0.05), the difference between the experimental group and the control group was statistically significant (P 0.05), and the gingival sulcus bleeding index, SBI) of the experimental group was significantly lower than that of the control group. There was a significant decrease in the depth of probing (P 0.05), from 4.42 卤0.58 and 4.77 卤1.45mm to 1.21 卤0.58 and 2.52 卤0.7 mm, respectively. There was significant difference between the experimental group and the control group (P 0.05), and the depth of bone loss in the experimental group was significantly lower than that in the control group (P < 0.05). DSBs decreased significantly from 3.35 卤0.70mm to 2.21 卤0.90mm. The difference between the experimental group and the control group was statistically significant (P 0.05). In the experimental group, a large number of new bone formation, and bone integration with the implant, the control group new bone formation was less. Conclusion: low temperature plasma jet combined with curettage is effective in the treatment of dog periimplant inflammation, improves clinical symptoms, reduces bacteria around implant, and promotes the recombination of implant and alveolar bone.
【学位授予单位】：华中科技大学
【学位级别】：博士
【学位授予年份】：2012
【分类号】：R782.2;R-332

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