阴离子转运体Slc26a9在消化系统中的表达和功能及相关疾病的研究进展

发布时间：2018-05-27 07:06

  本文选题：Slca + 消化系统　； 参考：《重庆医学》2017年19期

【摘要】：正Slc26a9是新近发现的多功能阴离子转运家族中的一员,主要表达在肺~([1])和胃~([2])的黏膜上皮细胞上,通过不同的生理学功能模式参与调节氯离子(Cl~-)和碳酸氢根离子(HCO_3~-)的转运。目前,已有的研究发现Slc26a9在不同器官中有着不同的生理功能,并与某些疾病的发生关系密切,但其在消化道中研究较少。本文就Slc26a基因家族的分类情况,Slc26a9在不同组织器官中的表达和可能的功能模式,在消化系统中的表达
[Abstract]:Positive Slc26a9 is a member of the newly discovered multifunctional anion transport family, mainly expressed in the mucosal epithelial cells of lung tissue ([1]) and stomach ([2]). It is involved in the regulation of the transport of chloride ion (Cl-C) and bicarbonate ion (HCOS3) through different physiological functional models. At present, it has been found that Slc26a9 has different physiological functions in different organs and is closely related to the occurrence of some diseases, but it is less studied in the digestive tract. According to the classification of Slc26a gene family, the expression of Slc26a9 in different tissues and organs and its possible functional patterns, and its expression in digestive system are reviewed in this paper.
【作者单位】： 遵义医学院附属医院消化内科;贵州省消化疾病研究所;遵义医学院附属医院甲乳外科;
【基金】：国家自然科学基金资助项目(81560456,81660098,81572438) 贵州省科技计划项目(黔科合平台人才[2016]5608) 贵州省留学人员科技创新项目(黔人项目资助合同[2016]-14号)
【分类号】：R333
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本文编号：1940954