ToxoDB#17型弓形虫卵囊对昆明小鼠致病性的研究
发布时间：2018-08-09 06:59
【摘要】：目的为探究ToxoDB#17型弓形虫对昆明小鼠的致病特点。方法分别选择1个,1个,101个,102个,103个,104个,105个,106个ToxoDB#17型弓形虫卵囊灌胃小鼠,观察小鼠的临床症状,采用改良凝集试验、HE和IHC方法研究弓形虫的感染率,小鼠生存率及其大脑内的包囊数量。结果≥104个卵囊组小鼠在攻虫后出现一过性的精神沉郁,弓背,被毛逆立现象,其余组精神状态正常;≥102个卵囊可引起小鼠100%感染,感染小鼠的成囊率为2.38%(1/42),感染小鼠生存率为85.71%(36/42),存活时间≥360DPI。结论 ToxoDB#17型弓形虫对昆明小鼠的致病力弱,包囊形成率低。
[Abstract]:Objective to study the pathogenic characteristics of ToxoDB#17 Toxoplasma gondii on Kunming mice. Methods 1, 1, 101, 102, 103, 104, 105, 106 ToxoDB#17 type Toxoplasma gondii oocysts were perfused into the stomach, and the clinical symptoms of the mice were observed. The infection rate of Toxoplasma gondii was studied by modified agglutination test (HE) and IHC. Survival rate of mice and the number of cysts in the brain. Results the mice of 鈮，
本文编号：2173267
[Abstract]:Objective to study the pathogenic characteristics of ToxoDB#17 Toxoplasma gondii on Kunming mice. Methods 1, 1, 101, 102, 103, 104, 105, 106 ToxoDB#17 type Toxoplasma gondii oocysts were perfused into the stomach, and the clinical symptoms of the mice were observed. The infection rate of Toxoplasma gondii was studied by modified agglutination test (HE) and IHC. Survival rate of mice and the number of cysts in the brain. Results the mice of 鈮，
本文编号：2173267
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