核酸抗原免疫识别机制的研究进展
发布时间:2019-06-11 01:08
【摘要】:正1963年经研究发现DNA和RNA具有激活机体免疫系统的功能,但是约40年之后才逐渐意识到有核酸感受器的存在~([1-2])。2000年Toll样受体(Toll-like receptors,TLRs)被发现具有可识别核酸并激活相关免疫系统的功能,随后逐步阐明了TLR3、TLR7、TLR8和TLR9等免疫识别受体识别DNA或RNA的部分相关机制~([3])。体内核酸感受器识别的核酸可分为病原性核酸和自身组织受损释放的核酸。病原性核酸包括感染
[Abstract]:It was found that DNA and RNA had the function of activating the immune system in 1963, but it was only about 40 years later that they gradually realized the existence of nucleic acid receptors ([1 鈮,
本文编号:2496883
[Abstract]:It was found that DNA and RNA had the function of activating the immune system in 1963, but it was only about 40 years later that they gradually realized the existence of nucleic acid receptors ([1 鈮,
本文编号:2496883
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