银黄清肺胶囊联合左氧氟沙星治疗下呼吸道肺炎支原体感染的临床研究

发布时间：2017-12-30 17:40

本文关键词：银黄清肺胶囊联合左氧氟沙星治疗下呼吸道肺炎支原体感染的临床研究　出处：《中华中医药学刊》2016年06期 　论文类型：期刊论文

【摘要】：目的:研究银黄清肺胶囊联合左氧氟沙星治疗下呼吸道肺炎支原体感染的临床效果。方法:选取医院呼吸内科2013年1月—2015年8月收治的96例下呼吸道肺炎支原体感染的患者并将其按数字表法分为对照组和观察组,每组48例患者。对照组患者仅用左氧氟沙星治疗,观察组患者采用银黄清肺胶囊联合左氧氟沙星治疗。对比两组患者治疗效果,体温恢复时间、咽痛消失时间、胸片病灶消失时间、治愈时间,治疗前后外周血白细胞(WBC)与C-反应蛋白(CRP)的变化情况。结果:观察组治疗后的总有效率(93.75%)明显高于对照组的(79.17%),统计学有意义(P0.05);观察组患者治疗后体温恢复时间(3.25±0.71)d、咽痛消失时间(3.11±0.35)d、胸片病灶消失时间(4.91±0.65)d、治愈时间(5.13±2.41)d明显少于对照组(6.48±0.91)d、(6.15±0.15)d、(13.89±2.74)d、(8.95±6.66)d,具有统计学意义(P0.05);两组患者治疗后WBC、CRP水平较治疗前均降低,且观察组治疗后WBC(4.01±0.03)×10~9/L、CRP(4.58±0.08)mg/L水平明显低于对照组治疗后WBC(4.31±0.21)×10~9/L、CRP(5.24±2.28)mg/L水平,具有统计学意义(P0.05)。结论:下呼吸道肺炎支原体感染的患者采用银黄清肺胶囊联合左氧氟沙星治疗的效果显著,可以明显缩短体温恢复时间、咽痛消失时间、胸片病灶消失时间、治愈时间,安全性高,值得在临床上推广。
[Abstract]:Objective: To study the clinical effect of Yinhuang Qingfei capsule combined with levofloxacin in the treatment of lower respiratory tract infection of mycoplasma pneumonia. Methods: hospital from January 2013 to August 2015 were 96 cases of lower respiratory tract mycoplasma infection and the patients were randomly divided into control group and observation group, 48 patients in each group. The control group only with levofloxacin treatment, observation group were treated with Yinhuang Qingfei capsules combined with levofloxacin in the treatment. The treatment effect were compared between the two groups, the recovery time of body temperature, throat disappear time, chest lesions disappeared time, healing time, before and after the treatment of peripheral white blood cell (WBC) and C- reactive protein (CRP) were observed. Results: after treatment, the total efficiency (93.75%) was significantly higher than the control group (79.17%), with statistical significance (P0.05); patients in the observation group after treatment, temperature recovery time (3.25 + 0.71) d, sore throat The disappearance time of (3.11 + 0.35) d, the disappearance time of chest lesions (4.91 + 0.65) d, the cure time (5.13 + 2.41) d was significantly less than the control group (6.48 + 0.91) d, (6.15 + 0.15) d, (13.89 + 2.74) d, (8.95 + 6.66) d, with statistical significance (P0.05); the two groups of patients after treatment of WBC, CRP levels were decreased significantly compared with before treatment, and the observation group after treatment, WBC (4.01 + 0.03) * 10~9/L, CRP (4.58 + 0.08) mg/L levels were significantly lower than the control group after treatment WBC (4.31 + 0.21) * 10~9/L, CRP (5.24 + 2.28) mg/L level. With statistical significance (P0.05). Conclusion: lower respiratory tract infection of mycoplasma pneumonia treated with Yinhuang Qingfei capsules combined with levofloxacin in the treatment of a significant effect, can significantly shorten the recovery time of body temperature, throat disappear time, chest lesions disappeared time, cure time, high safety, worthy of clinical popularization.

【作者单位】：绍兴市人民医院(浙江大学绍兴医院);
【基金】：浙江省中医药科学研究基金A类项目(2013ZA125)
【分类号】：R56
【正文快照】： Yinhuang Qingfei Capsule Combined with Levofloxacin in Treatment ofLower Respiratory Tract Infection Patients with Mycoplasma PneumoniaHE Wei,LI Minghui,SU Meixia,MA Jianyong(Shaoxing People's Hospital,Shaoxing Hospital of Zhejiang University,Shaoxing 31

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