左氧氟沙星与头孢哌酮治疗下呼吸道感染的临床评价

发布时间：2018-01-17 02:25

本文关键词：左氧氟沙星与头孢哌酮治疗下呼吸道感染的临床评价　出处：《中华医院感染学杂志》2015年21期 　论文类型：期刊论文

【摘要】：目的探讨左氧氟沙星与头孢哌酮治疗急性轻度细菌性下呼吸道感染的临床效果和安全性,为临床治疗提供参考依据。方法选取2011年4月-2014年3月193例急性轻度细菌性下呼吸道感染患者,随机分为两组,A组95例给予左氧氟沙星治疗,B组98例给予头孢哌酮治疗;对两组患者治疗3d后的临床效果进行评价,并记录两组患者不良反应发生率。结果患者治疗有效率A组为90.53%、B组为75.51%;不良反应发生率A组为2.11%、B组为5.10%;A组治疗有效率明显高于B组,不良反应发生率明显低于B组,两组比较差异有统计学意义(P0.05)。结论左氧氟沙星用于治疗急性轻度细菌性下呼吸道感染患者具有良好的治疗效果,且较少发生不良反应,是一种安全有效的抗菌药物。
[Abstract]:Objective to investigate the clinical efficacy and safety of levofloxacin and cefoperazone in the treatment of acute mild bacterial lower respiratory tract infection. Methods from April 2011 to March 2014, 193 patients with acute mild bacterial lower respiratory tract infection were randomly divided into two groups. Group A (95 cases) were treated with levofloxacin and group B (98 cases) were treated with cefoperazone. The clinical effects of the two groups were evaluated 3 days after treatment and the incidence of adverse reactions was recorded. Results the effective rate of treatment in group A was 90.53 and that in group B was 75.51; The incidence of adverse reactions in group A was 2.11 and that in group B was 5.10; The effective rate of treatment in group A was significantly higher than that in group B, and the incidence of adverse reactions in group A was significantly lower than that in group B. Conclusion levofloxacin has a good therapeutic effect on patients with acute mild bacterial lower respiratory tract infection and less adverse reactions. It is a safe and effective antimicrobial agent.
【作者单位】：河南省胸科医院呼吸二病区;
【基金】：河南省卫生厅基金资助项目(HW-2012B-031)
【分类号】：R56
【正文快照】： 下呼吸道感染是临床常见疾病,很多患者急性起病,表现为咳嗽、咳痰症状,早期给予及时而有效的治疗,可以避免引起严重的呼吸功能障碍或者全身感染,甚至危及生命[1]。本研究通过给予193例急性轻度细菌性下呼吸道感染患者不同抗菌药物治疗,现将结果报道如下。1资料与方法1.1临床资

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