RICU慢性阻塞性肺疾病患者下肢深静脉血栓形成的流行病学分析

发布时间：2018-02-16 18:03

本文关键词： 呼吸重症监护病房(RICU) 慢性阻塞性肺疾病下肢深静脉血栓　出处：《西安交通大学学报(医学版)》2017年03期 　论文类型：期刊论文

【摘要】：目的探讨呼吸重症监护病房(respiratory intensive care unit,RICU)慢性阻塞性肺疾病(chronic obstructive pulmonary disease,COPD)患者下肢深静脉血栓形成(deep vein thrombosis,DVT)的发病率及相关危险因素。方法连续收集我院RICU自2015年1月至2015年12月住院的COPD患者204例,收集患者的基本临床资料,住院24~48h内行床旁双下肢静脉超声检查。将患者分为DVT组及非DVT组,并对两组患者的临床资料进行分析比较,多因素Logistic回归分析相关危险因素。ROC曲线分析评价实验指标的疾病识别能力。结果 204例患者中有39例发生DVT,总体发病率为19.1%。DVT组患者的D二聚体较非DVT组明显升高(P0.001),而两组患者在年龄、性别、吸烟史、基础疾病、其他实验室检查等方面无统计学差异。D二聚体的ROC曲线下面积为0.787,具有统计学差异,其cut off值为1.985mg/L,灵敏度为0.641,特异度为0.817。结论 RICU中COPD患者D二聚体升高与DVT的发生密切相关。
[Abstract]:Objective to investigate the incidence and risk factors of deep vein thromboembolism (DVT) in patients with intensive care obstructive pulmonary disease of chronic obstructive pulmonary disease (COPD) in respiratory intensive care unit (RICU). Methods RICU from January 2015 to 2015 was collected continuously in our hospital. In December, 204 COPD patients were hospitalized, The patients were divided into DVT group and non-#en1# group. The clinical data of the two groups were analyzed and compared. Results 39 out of 204 patients developed DVT, and the overall incidence rate was 19.1. the D-dimer level in DVT group was significantly higher than that in non-#en1# group. P 0.001, while the two groups of patients were at age, There was no statistical difference in sex, smoking history, basic diseases and other laboratory tests. The area under the ROC curve of D dimer was 0.787, which had statistical difference. The cut off value was 1.985 mg / L, the sensitivity was 0.641, and the specificity was 0.817.Conclusion the increase of D dimer in COPD patients in RICU is closely related to the occurrence of DVT.
【作者单位】：西安交通大学医学部第一附属医院急诊科;西安交通大学医学部第一附属医院呼吸与危重症医学科;
【基金】：国家自然科学基金资助项目(No.81400039)~~
【分类号】：R563.9

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