注射期末耐多药肺结核的临床疗效分析

发布时间：2018-03-03 00:21

本文选题：耐多药　切入点：结核　出处：《现代预防医学》2014年07期 　论文类型：期刊论文

【摘要】：目的了解耐多药肺结核患者(MDRTB)临床疗效及其转归,以进一步提高对注射期重要性的认识,探讨MDRTB患者管理办法。方法选取2009年10月至2011年1月南通市第六人民医院收治的经南通市疾病预防控制中心和南通市第六人民医院药物敏感试验证实的MDRTB患者76例,分为注射期末阳性组、阴性组和未查组,观察3组间临床疗效、不良反应、转归等。结果注射期末痰菌阴性组痰菌阴转率、病灶吸收率、空洞闭合率均明显高于痰菌阳性组和未查组,而不良反应发生率在3组间差异无统计学意义。涂阴组治愈率明显高于涂阳组和未查组,差异有统计学意义(χ2=23.276,P0.05)。结论 MDRTB患者中,注射期末痰菌阴性组临床疗效及转归明显好于涂阳组和未查组。重视规范MDRTB患者注射期治疗及定期监测,加强督导管理,可提高治愈率。
[Abstract]:Objective to investigate the patients with multi drug resistant pulmonary tuberculosis (MDRTB) clinical efficacy and prognosis, to further improve the understanding of the importance of the injection period, measures for the management of MDRTB patients. Methods 76 cases of the Sixth People's Hospital from October 2009 to January 2011 in Nantong city by the Nantong Municipal Center for disease control and prevention, Nantong city sixth people's hospital confirmed the drug sensitive test MDRTB patients were divided into the final injection of positive group and negative group and not check group, observe 3 groups of clinical curative effects, adverse reactions and outcomes. Results the final injection of sputum negative sputum, lesion absorption rate, cavity closure rate was significantly higher than that of sputum positive group and no check group, and adverse reaction rate in the absence of significant difference between the 3 groups. The cure rate of smear negative group was significantly higher than that of smear positive group and the research group, the difference was statistically significant (2=23.276, P0.05). Conclusion in MDRTB patients, the final injection of sputum The clinical efficacy and prognosis of the negative group were significantly better than those of the smear Yang Group and the non check group. The importance of standardizing the injection period and regular monitoring of MDRTB patients and strengthening the supervision and management can improve the cure rate.

【作者单位】：江苏省南通市疾病预防控制中心;江苏省南通市第六人民医院;
【分类号】：R521

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