肾脏清除率对重症肺部感染患者机体内稳可信谷浓度影响的研究

发布时间：2018-03-04 20:04

  本文选题：稳可信　切入点：谷浓度　出处：《中国地方病防治杂志》2017年07期 　论文类型：期刊论文

【摘要】：正近些年来,肾清除率增加对抗菌药血药浓度的影响逐渐受到关注。有研究称,重症感染患者可能会发生肾清除率增加,从而影响抗菌治疗效果[1]。因此了解肾清除率对稳可信血药浓度的影响对于指导临床合理用药非常重要。本研究分析了老年重症肺部感染患者血液中稳可信谷浓度,旨在探讨肾清除率对于谷浓度的影响。1资料与方法1.1纳入与排除标准纳入标准:(1)符合重症肺炎诊断的患者;(2)MRSA感染并接受稳可信治疗的患者;(3)患者年龄≥
[Abstract]:In recent years, the effect of increased renal clearance on the blood concentration of antimicrobial agents has become increasingly concerned. Some studies have suggested that patients with severe infections may have increased renal clearance. Therefore, it is very important to understand the effect of renal clearance rate on stable and credible serum drug concentration in order to guide the rational use of drugs in clinic. This study analyzed the stable and credible valley concentration in blood of elderly patients with severe pulmonary infection. Objective to investigate the effect of renal clearance on valley concentration. 1 data and methods 1.1 inclusion and exclusion criteria: 1) age 鈮，

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