肺癌合并慢性阻塞性肺疾病临床特征及治疗策略的研究

发布时间：2018-03-05 17:05

本文选题：原发性肺癌　切入点：阻塞性肺炎　出处：《中国实用内科杂志》2014年S1期 　论文类型：期刊论文

【摘要】：目的为了探索COPD和肺癌之间的关系,以及两病共存患者的临床特征及COPD对肺癌患者预后的影响,本研究旨在观察COPD合并肺癌患者的临床特征、诊断、治疗及预后。方法回顾性研究2010年3月至2012年12月于上海交大医学院附属瑞金医院初诊的原发性肺癌患者601例,收集他们的一般资料、临床特征、诊疗方式及预后情况。分为单纯肺癌组及肺癌合并COPD组。结果单纯肺癌组449例,肺癌合并COPD组152例。高龄、男性、既往存在吸烟史、影像学表现为阻塞性肺炎、肺不张、胸腔积液、病理类型为鳞癌的肺癌患者较易并发COPD。肺癌合并COPD组患者最终多选择化疗及支持治疗的。两组化疗患者在治疗预后上也存在统计学差异,肺癌合并COPD组的无疾病进展时间比单纯肺癌组更短(P0.05)。结论肺癌合并COPD患病率与患者的年龄、吸烟史、肺癌病理类型及影像学表现均有关系。肺癌合并COPD患者的预后将明显不良。
[Abstract]:Objective to explore the relationship between COPD and lung cancer, the clinical characteristics of patients with two diseases and the influence of COPD on the prognosis of patients with lung cancer, the purpose of this study was to observe the clinical characteristics and diagnosis of COPD patients with lung cancer. Methods A retrospective study of 601 patients with primary lung cancer from March 2010 to December 2012 in Ruijin Hospital affiliated to Shanghai Jiaotong University Medical College was conducted and their general data and clinical features were collected. Methods of diagnosis and treatment and prognosis were divided into simple lung cancer group and lung cancer combined with COPD group. Results there were 449 cases of lung cancer group and 152 cases of lung cancer combined with COPD group. Patients with lung cancer with squamous cell carcinoma and pleural effusion were more likely to be complicated with cod. The patients with lung cancer combined with COPD were more likely to choose chemotherapy and support therapy. There were also statistical differences in the treatment prognosis between the two groups. Conclusion the incidence of lung cancer with COPD is related to the age, smoking history, pathological type and imaging manifestation of lung cancer with COPD. The prognosis of lung cancer patients with COPD will be significantly poor.
【作者单位】：上海交通大学医学院附属瑞金医院呼吸内科;
【分类号】：R563.9;R734.2

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