支气管扩张症患者死亡相关危险因素分析

发布时间：2018-03-12 14:53

  本文选题：支气管扩张症　切入点：危险因素　出处：《中国呼吸与危重监护杂志》2016年06期 　论文类型：期刊论文

【摘要】：目的探讨支气管扩张症患者死亡相关危险因素。方法收集2011年1月至2013年12月因支气管扩张症住院且有完整资料的283例患者,随访至2015年10月,分析患者年龄、性别、体重指数(body mass index,BMI)、吸烟史、呼吸困难评分、影像学资料,痰培养,血气分析、肺功能等指标,对影响患者预后的危险因素进行COX回归分析。结果 283例患者中好转231例,死亡52例,患者1、2、3、4年累积生存率分别为97%、86%、71%、45%;COX回归分析显示年龄≥70岁(RR=2.222,95%CI 1.145~4.314)、BMI18.5 kg/m~2(RR=2.328,95%CI 1.205~4.497)、肺HRCT累及肺叶数≥3个(RR=0.382,95%CI 0.188~0.774)、FEV1%pred70%(RR=1.032,95%CI 0.923~1.180)是影响支气管扩张症患者死亡的独立危险因素(均P0.05)。结论支气管扩张症患者死亡与多种因素相关,早期识别危险因素有利于支气管扩张症管理。
[Abstract]:Objective to investigate the risk factors related to death in patients with bronchiectasis. Methods from January 2011 to December 2013, 283 patients with bronchiectasis with complete data were collected and followed up until October 2015 to analyze the age and sex of the patients. Body mass index (BMI), smoking history, dyspnea score, imaging data, sputum culture, blood gas analysis and pulmonary function were analyzed by COX regression analysis. 52 deaths, The cumulative survival rates of patients with 1, 2, 3 and 4 years were 97 / 2 / 866 / 71and 75 / 45 respectively. The results of Cox regression analysis showed that RRN 2.22295 CI 1.1452.22295 CI 1.1454.31445 BMI 18.5 kg / kg RMI 2.3289595 CI 1.2054.497, lung HRCT involvement and the number of pulmonary lobes 鈮，

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