特发性肺纤维化急性加重10例

发布时间：2018-03-16 13:40

本文选题：特发性肺纤维化急性加重　切入点：影像学　出处：《中国老年学杂志》2015年05期 　论文类型：期刊论文

【摘要】：目的分析特发性肺纤维化急性加重(AEIPF)病例的临床特点、影像学表现及预后。方法收集10例AEIPF患者的诊治资料,回顾分析其临床表现、肺部CT特点及激素治疗前后变化情况,进一步阐明AEIPF患者临床特点、肺部CT表现与激素治疗的相关性。结果 10例AEIPF患者以快速发展的呼吸困难为主要症状,体检双肺可闻及Velcro音和杵状指,胸部影像学表现为在原有网格或蜂窝肺的背景下出现了新的双侧磨玻璃样异常改变和(或)实变阴影,经冲击剂量激素治疗后,4例周边型患者生存,2例周边型、2例多灶型及2例弥漫型患者死亡。结论 AEIPF患者临床影像学表现为新出现的病灶可呈周边型、多灶型或弥漫型;周边型预后较好,弥漫型预后最差;经冲击剂量激素治疗4例生存,6例死亡。
[Abstract]:Objective to analyze the clinical features, imaging manifestations and prognosis of patients with acute exacerbation of idiopathic pulmonary fibrosis (AEIPF). Methods Ten patients with AEIPF were collected and their clinical manifestations, pulmonary CT features and changes before and after hormone therapy were retrospectively analyzed. The clinical features of AEIPF patients and the correlation between lung CT findings and hormone therapy were further elucidated. Results Ten patients with AEIPF had rapid developing dyspnea as their main symptoms. Both lungs could be heard Velcro sound and clubbing fingers in physical examination. Chest imaging showed new bilateral glass-like abnormalities and / or solid shadows in the background of the original mesh or honeycomb lung. After shock dose hormone therapy, 4 patients with peripheral type survived 2 patients with peripheral type and 2 patients with diffuse type died. Conclusion the clinical imaging findings of AEIPF patients may be peripheral type, multi-focus type or diffuse type. The prognosis of peripheral type was better than that of diffuse type, and 4 cases survived and 6 cases died.
【作者单位】：内蒙古民族大学附属医院;
【基金】：内蒙古自治区自然科学基金项目(2012MS1170)
【分类号】：R563.9

【参考文献】