肺炎支原体感染对脑梗死的相关性研究

发布时间：2018-03-17 21:26

本文选题：肺炎支原体　切入点：脑梗死　出处：《中华医院感染学杂志》2014年08期 　论文类型：期刊论文

【摘要】：目的分析肺炎支原体(MP)感染与脑梗死的相关性,以便临床更好地预防控制脑梗死的发生。方法选取2010年1月-2012年12月医院就诊的脑梗死患者60例,30例患者作为传统危险因素组,对就诊不存在传统脑梗死危险因素且符合脑梗死诊断的患者30例作为无传统因素组,随机选取健康体检人员30名作为正常组;用ELISA法测定所有研究对象的抗MP-IgG、IgM抗体,并比较抗MP-IgG、IgM抗体的阳性率,数据采用SPSS 16.0进行分析。结果传统危险因素组对抗MP-IgG抗体和抗MP-IgM抗体的阳性率分别为16.7%、3.3%,无传统危险因素组对抗MP-IgG抗体和抗MP-IgM抗体的阳性率分别为20.0%、10.0%;两组比较差异有统计学意义(P0.05),肺炎支原体感染在两组间差异有统计学意义。结论肺炎支原体感染可能为脑梗死发生发展的独立因素,临床应该针对肺炎支原体感染进行预防及治疗。
[Abstract]:Objective to analyze the correlation between Mycoplasma pneumoniae (MPP) infection and cerebral infarction in order to prevent and control the occurrence of cerebral infarction. Methods 60 patients with cerebral infarction from January 2010 to December 2012 were selected as the traditional risk factors group. Thirty patients who had no traditional risk factors of cerebral infarction and who were in accordance with the diagnosis of cerebral infarction were selected as the control group and 30 healthy persons as the normal group. The anti-MP-IgG IgM antibody of all the subjects was determined by ELISA method. The positive rate of anti-MP-IgG antibody was compared. Results the positive rates of anti MP-IgG antibody and anti MP-IgM antibody in the traditional risk factor group were 16.773% and 20.0% respectively in the group without traditional risk factors, and 20.0% and 10.0% in the group without traditional risk factors, respectively. There was significant difference in mycoplasma pneumoniae infection between the two groups. Conclusion Mycoplasma pneumoniae infection may be an independent factor for the occurrence and development of cerebral infarction. Clinical prevention and treatment of mycoplasma pneumoniae infection should be carried out.
【作者单位】：杭州红十字会医院神经内科;南京医科大学;
【基金】：江苏省教育厅自然科学研究基金资助项目(10KJB310005)
【分类号】：R743.3;R563.1

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