糖尿病并发获得性肺部感染患者病原菌分布及药物敏感性研究

发布时间：2018-03-25 10:37

本文选题：糖尿病　切入点：医院获得性肺炎　出处：《中华医院感染学杂志》2017年18期

【摘要】：目的探讨糖尿病并发获得性肺部感染患者的病原菌分布及药物敏感性,为临床治疗合理选择抗菌药物提供依据。方法选取2013年1月-2016年12月医院收治的136例2型糖尿病合并医院获得性肺炎患者,采集患者痰液标本,进行菌株鉴定和药敏试验。结果 136例糖尿病合并医院获得性肺炎患者中,检出病原菌158株,其中革兰阴性菌99株占62.66%,以肺炎克雷伯杆菌和铜绿假单胞菌为主;革兰阳性菌46株占29.11%,以金黄色葡萄球菌和肺炎链球菌为主;真菌13株占8.23%;肺炎克雷伯菌和铜绿假单胞菌对亚胺培南、美罗培南、氨曲南、左氧氟沙星、阿米卡星、氯霉素耐药率均10.00%,金黄色葡萄球菌和肺炎链球菌对利奈唑胺、万古霉素、替考拉宁耐药率均10.00%。结论革兰阴性菌是糖尿病合并医院获得性肺炎的主要致病菌,临床治疗时,根据药敏试验结果合理选择抗菌药物治疗。
[Abstract]:Objective to investigate the distribution of pathogenic bacteria and drug sensitivity in patients with diabetes mellitus complicated with acquired pulmonary infection. Methods 136 patients with type 2 diabetes mellitus complicated with nosocomial pneumonia from January 2013 to December 2016 were selected and their sputum samples were collected. Results 158 strains of pathogenic bacteria were detected in 136 patients with diabetes mellitus and hospital acquired pneumonia, of which 99 strains were Gram-negative bacteria, mainly Klebsiella pneumoniae and Pseudomonas aeruginosa. Forty-six Gram-positive bacteria accounted for 29.11um, mainly Staphylococcus aureus and Streptococcus pneumoniae; 13 fungi accounted for 8.23; Klebsiella pneumoniae and Pseudomonas aeruginosa for imipenem, meropenem, aztreonam, levofloxacin, amikacin, The resistance rates of Staphylococcus aureus and Streptococcus pneumoniae to linazolamine, vancomycin and teicoplanin were 10.00. Conclusion Gram-negative bacteria are the main pathogens of diabetes mellitus with hospital acquired pneumonia. According to the results of drug sensitivity test, antimicrobial therapy was reasonably selected.
【作者单位】：山东省无棣县人民医院内分泌科;
【分类号】：R563.1;R587.2

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