1例脑梗死伴肺部感染患者白细胞Pelger-Huёt异常

发布时间：2018-03-25 12:37

  本文选题：中性粒细胞　切入点：Pelger-Huёt　出处：《临床检验杂志》2014年08期

【摘要】：正Pelger-Huёt异常(Pelger-Huёt anomaly,PHA)是一种先天或后天多种原因引起的白细胞畸形,细胞形态在显微镜下主要表现为中性粒细胞核分叶困难、分2叶甚至完全不分叶和过度的染色质凝聚的现象。PHA可以是常染色体显性遗传,与核纤层蛋白B受体(lamin B receptor,LBR)的基因(LBR)突变密切相关;也可以是后天获得,即假性PHA,又称获得性
[Abstract]:Positive Pelger-Hu abnormality (Pelger-Hu anomaly) is a kind of white blood cell malformation caused by congenital or acquired leukocyte malformation. Under microscope, the cell morphology is mainly characterized by the difficulty of neutrophil nuclear lobulation. PHA may be an autosomal dominant inheritance, closely related to the mutation of the nuclear lamin B receptor LBRs gene, or acquired, or acquired, or acquired.
【作者单位】： 上海交通大学医学院附属仁济医院检验科;
【分类号】：R743.3;R563.1
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本文编号：1663163