ADAM33基因rs512625、rs511898、rs528557多态性与大鱼际掌纹特应征的相关性研究

发布时间：2018-04-01 06:14

  本文选题：哮喘　切入点：大鱼际掌纹特应征　出处：《中华中医药杂志》2017年12期

【摘要】：目的:探讨ADAM33基因多态性与青岛地区汉族成人哮喘患者大鱼际掌纹特应征的相关性。方法:引入计算机识别系统,实现大鱼际掌纹特应征客观量化分级,采用SNa Pshot方法检测400例哮喘患者和200例正常对照的ADAM33基因rs512625、rs511898和rs528557共3个多态位点的基因型和等位基因频率。结果:ADAM33基因rs512625、rs511898和rs528557的基因型频率在掌纹阴性组和掌纹阳性组间差异无统计学意义。结论:ADAM33基因rs512625、rs511898和rs528557多态性与大鱼际掌纹特应征不存在相关性。
[Abstract]:Objective: to investigate the association between ADAM33 gene polymorphism and the application of palmar palmprint in adult asthmatic patients in Qingdao. Methods: a computer recognition system was introduced to realize the objective and quantitative classification of the application of the hypothenar palmprint. The genotypes and alleles of ADAM33 gene rs512625rs511898 and rs528557 in 400 asthmatic patients and 200 normal controls were detected by SNa Pshot method. Results the genotype frequencies of rs512625rs511898 and rs528557 of the ADAM33 gene rs512625rs511898 were detected in palmprint negative group and palmprint type group. Conclusion there is no correlation between the rs512625rs511898 and rs528557 polymorphisms of the 1: ADAM33 gene and the application of thenar palmprint.
【作者单位】： 青岛市中医医院肺病科;
【基金】：国家自然科学基金项目(No.30873315) 山东省中医药科技发展计划项目(No.2015-354)~~
【分类号】：R562.25
，

本文编号：1694306