重症肿瘤患者嗜麦芽寡养单胞菌肺部感染危险因素分析

发布时间：2018-04-04 20:22

  本文选题：肿瘤　切入点：医院获得性肺炎　出处：《中华医院感染学杂志》2014年06期

【摘要】：目的分析重症肿瘤患者嗜麦芽寡养单胞菌肺炎高危因素及细菌耐药性分析,为指导临床治疗嗜麦芽寡养单胞菌肺炎提供可靠依据。方法收集专科医院医院ICU 2008年12月-2011年6月312例重症肿瘤患者临床资料,采用回顾性调查方法调查嗜麦芽寡养单胞菌肺部感染危险因素,采用ATB细菌鉴定系统进行鉴定及药敏试验,采用SPSS10.0统计软件进行统计分析,多因素相关分析应用logistic回归分析。结果肿瘤专科医院ICU肿瘤重症患者发生嗜麦芽寡养单胞菌肺炎32例,发生率为10.3%,APACHEⅡ评分≥16分、呼吸机通气时间7d、骨髓抑制是嗜麦芽寡养单胞菌肺炎发生的独立危险因素,OR值分别为9.860、3.061及2.625,病死率为40.6%;耐药率最高的是亚胺培南、头孢唑林、头孢噻肟及妥布霉素均为100.0%,最低的是头孢哌酮/舒巴坦及哌拉西林/他唑巴坦,分别为12.0%及8.5%。结论有效治疗原发病,减少机械通气时间、纠正骨髓抑制可有效减少肿瘤患者嗜麦芽寡养单胞菌肺炎发生率。
[Abstract]:Objective to analyze the high risk factors and bacterial resistance of severe tumor patients with pneumonia of oligotrophomonas maltophilia so as to provide a reliable basis for clinical treatment of pneumonia of oligotrophomonas maltophilia.Methods the clinical data of 312 patients with severe tumor in ICU from December 2008 to June 2011 were collected, and the risk factors of pulmonary infection of Mycotrophomonas maltophilia were investigated retrospectively.ATB bacterial identification system was used for identification and drug sensitivity test, SPSS10.0 software was used for statistical analysis, and logistic regression analysis was used for multivariate correlation analysis.Results 32 patients with severe ICU tumor were found to have pneumonia in maltophilia, the incidence rate was 10.3% and Apache 鈪，

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