老年糖尿病患者院内获得性肺部感染的临床特征分析

发布时间：2018-04-07 16:48

本文选题：老年糖尿病　切入点：院内获得性肺部感染　出处：《中华医院感染学杂志》2015年09期

【摘要】：目的对老年糖尿病患者院内获得性肺部感染的临床特征进行分析,并提出相应的防治措施,以降低感染率。方法选取2011年6月-2013年6月医院收治的300例老年糖尿病患者,观察其发生院内获得性肺部感染的相关实验室指标,并制定相关防治措施。结果 300例糖尿病患者中发生院内获得性肺部感染43例,感染率为14.3%;患者的年龄、住院时间、侵入性操作、糖化血红蛋白水平是老年糖尿病患者发生院内获得性肺部感染的重要影响因素(P0.05);43例肺部感染患者入院48h呼吸系统特征分布显示,咳嗽、咳痰患者30例占69.8%,发热20例占46.5%,肺实变体征、Up音患者33例占76.7%,片状、斑状侵润性阴影或肺纹理增多等类圆形病灶患者38例占88.4%,血白细胞10×109/L或中性粒细胞70.0%患者23例占53.5%;43例肺部感染患者痰标本培养分离病原菌阳性23例,阳性率为53.5%;23例阳性标本共分离出病原菌29株,其中革兰阴性菌19株占65.52%,革兰阳性菌6株占20.69%,真菌4株占13.79%。结论老年糖尿病患者院内获得性肺部感染受多种因素影响,临床应及时进行诊断治疗,有效减少不良反应的发生。
[Abstract]:Objective to analyze the clinical features of nosocomial pulmonary infection in elderly patients with diabetes mellitus and to put forward corresponding preventive and therapeutic measures to reduce the infection rate.Methods 300 elderly patients with diabetes were selected from June 2011 to June 2013. The laboratory indexes of nosocomial pulmonary infection were observed and the preventive and therapeutic measures were made.Results there were 43 cases of nosocomial pulmonary infection in 300 patients with diabetes, and the infection rate was 14.3%.The level of glycosylated hemoglobin is an important influencing factor of nosocomial pulmonary infection in elderly patients with diabetes mellitus.There were 30 patients with expectoration (69.8%), 20 cases with fever (46.5 cases), 33 cases with signs of pulmonary consolidation (76.7%) and 76.7 cases (76.7%).38 patients (88.4) with round lesions such as macular shadow or increased pulmonary textures, 23 patients (23 / 43) with leucocyte 10 脳 10 9 / L or neutrophil 70.0% (23 / 43) with pulmonary infection were positive for pathogenic bacteria in sputum culture, 23 cases were positive for pathogenic bacteria in sputum culture, and 23 cases were positive for pathogenic bacteria in sputum culture of 43 patients with pulmonary infection.A total of 29 pathogenic bacteria were isolated from 23 positive specimens, including 19 Gram-negative bacteria (65.52), 6 Gram-positive bacteria (20.69) and 4 fungi (13.79).Conclusion the nosocomial pulmonary infection in elderly diabetic patients is affected by many factors.
【作者单位】：潍坊医学院药学院;
【基金】：山东省自然科学基金资助项目(ZR2014HL106) 山东省医药卫生科技基金资助项目(2014WS0467)
【分类号】：R587.1;R563.1

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