穴位注射卡介菌多糖核酸治疗支气管哮喘疗效观察

发布时间：2018-04-13 07:36

本文选题：支气管哮喘 + 穴位注射　；参考：《针刺研究》2015年01期

【摘要】：目的:观察卡介菌多糖核酸不同给药途径对支气管哮喘疗效的差异。方法:将60例支气管哮喘患者随机分为穴位注射组30例和肌肉注射组30例。穴位注射组将卡介菌多糖核酸注射液于双侧肺俞穴处行穴位注射,前15d每日1次,双侧肺俞穴各注射1mL,15d以后隔日注射1次,连续用药3个月;肌肉注射组将卡介菌多糖核酸注射液2mL注射于一侧臀部,给药时间同穴位注射组。比较治疗后两组肺功能及免疫球蛋白情况及停药3个月后两组症状、体征积分及哮喘控制测试(ACT)得分。结果:两组治疗后肺功能、IgE、IgG、症状体征积分、ACT得分均较治疗前改善(P0.01),但穴位注射组的改善作用优于肌肉注射组(P0.01,0.05),停药3个月后穴位注射组症状体征积分、ACT得分仍优于肌肉注射组(P0.01)。结论:穴位注射较肌肉注射卡介菌多糖核酸能更快速、持久控制患者症状、体征,能更显著改善肺功能、降低IgE,是治疗支气管哮喘的有效方案。
[Abstract]:Objective: to observe the effect of BCG polysaccharide nucleic acid on bronchial asthma.Methods: 60 patients with bronchial asthma were randomly divided into acupoint injection group (n = 30) and intramuscular injection group (n = 30).In the acupoint injection group, BCG polysaccharide nucleic acid injection was injected at both sides of Feshu point, once a day on the first 15 days, and once every other day after 15 days of injection at the bilateral Feshu acupoints for 3 months.In intramuscular injection group, BCG polysaccharide nucleic acid injection (2mL) was injected into one hip at the same time as acupoint injection group.The pulmonary function and immunoglobulin were compared between the two groups after treatment, and the scores of symptoms, physical signs and asthma control test (ACT) were compared between the two groups after 3 months of withdrawal.Results: after treatment, the scores of IgEG, symptom and sign score and ACT in both groups were improved compared with those before treatment, but the improvement effect of acupoint injection group was better than that of intramuscular injection group (P0.010.05), and the ACT score of acupoint injection group was still better than that of intramuscular injection group after 3 months.Conclusion: point injection is more rapid than intramuscular injection of BCG polysaccharide nucleic acid, can control symptoms and signs of patients, can significantly improve pulmonary function and reduce IgE, so it is an effective treatment for bronchial asthma.
【作者单位】：南昌大学第二附属医院中医科;
【基金】：江西省卫生厅中医药科研基金项目(No.2011A070)
【分类号】：R562.25

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