阻塞性睡眠呼吸暂停低通气综合征合并高血压患者早晨血压高峰出现率及出现时间研究

发布时间：2018-04-17 01:29

  本文选题：阻塞性 + 睡眠呼吸暂停　； 参考：《中国全科医学》2014年25期

【摘要】：目的探讨阻塞性睡眠呼吸暂停低通气综合征(OSAHS)合并高血压患者动态血压特点,尤其是早晨血压高峰出现率及出现时间,并分析其相关因素。方法选取2011年1月—2012年12月因打鼾在广西壮族自治区人民医院睡眠呼吸疾病诊疗中心行多导睡眠图(PSG)检测确诊为OSAHS患者,根据有无高血压分为OSAHS高血压组和单纯OSAHS组。同时,在高血压门诊随机选取无打鼾的高血压患者为对照1组(单纯高血压组),在体检中心和我院职工中随机招募无打鼾无高血压者为对照2组(正常组)。对4组人群行24 h动态血压监测并对其数据进行分析,比较4组非杓型血压发生率、早晨血压高峰出现率和出现的时间。结果 OSAHS高血压组非杓型血压发生率为86.4%(38/44),单纯OSAHS组为79.1%(91/115),单纯高血压组为45.8%(11/24),正常组为23.3%(7/30),4组比较差异有统计学意义(P0.01);OSAHS高血压组早晨血压高峰发生率为84.1%(37/44),单纯OSAHS组为50.4%(58/115),单纯高血压组为37.5%(11/24),正常组为26.7%(8/22),4组比较差异有统计学意义(P0.01)。早晨血压高峰出现时间:OSAHS高血压组5:00~6:00出现率最高,为86.4%(38/44);单纯OSAHS组5:00~6:00出现率最高,为60.9%(70/115);单纯高血压组7:00~8:00出现率最高,为37.5%(5/24);正常组在早晨各时段出现率无差异。结论 OSAHS高血压组与单纯OSAHS组、单纯高血压组、正常组全天血压变化规律存在差异,OSAHS高血压组非杓型血压及早晨血压高峰发生率明显增加,OSAHS高血压组、单纯OSAHS组早晨血压高峰出现时间比单纯高血压组出现时间提前。
[Abstract]:Objective to investigate the characteristics of ambulatory blood pressure (ABP) in patients with obstructive sleep apnea hypopnea syndrome (OSAHS) complicated with hypertension, especially the occurrence rate and time of morning peak blood pressure, and to analyze the related factors.Methods from January 2011 to December 2012, patients with OSAHS were diagnosed by polysomnography (PSG) in the diagnosis and treatment center of sleep respiratory diseases of Guangxi Zhuang Autonomous region people's Hospital for snoring. According to hypertension, they were divided into OSAHS hypertension group and simple OSAHS group.At the same time, the hypertension patients without snoring were randomly selected as control group (simple hypertension group), and those without snoring and hypertension were recruited randomly in physical examination center and staff of our hospital as control group (normal group).The 24 h ambulatory blood pressure monitoring was performed in 4 groups and the data were analyzed to compare the incidence of non dipper blood pressure in the four groups and the occurrence rate and time of peak blood pressure in the morning.Results the incidence of non-dipper blood pressure in the OSAHS hypertension group was 86.4 / 44, that in the simple OSAHS group was 79.1 / 91 / 115, that in the simple hypertension group was 45.8 / 24, and that in the normal group was 23.3 / 7 / 30 / 4. There was a statistically significant difference in the incidence of morning blood pressure peak in the hypertension group (84.1% 3744%), in the simple OSAHS group (50.458% / 115).In the hypertension group, there was a significant difference (P 0.01) between 37.5 / 24% and 26.7 / 22 / 24 of the normal group (P < 0.01).Morning blood pressure peak time: 5: 00: 6: 00 the highest rate was 86.4B / 44%; the OSAHS group had the highest rate of 5: 00 / 6: 00 (60.970 / 115); the simple hypertension group had the highest occurrence rate of 7: 00 / 800 (37.55524%); the normal group had no difference in the rate of occurrence at each time in the morning.Conclusion there is a significant difference between OSAHS hypertension group and simple OSAHS group, simple hypertension group, normal group. The incidence of non-dipper blood pressure and morning blood pressure peak in OSAHS hypertension group is significantly higher than that in OSAHS hypertension group.The onset time of peak blood pressure in OSAHS group was earlier than that in simple hypertension group.
【作者单位】： 广西壮族自治区人民医院 广西睡眠呼吸疾病诊疗中心;
【基金】：广西自然科学基金项目(桂科自0991211)
【分类号】：R563.8
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本文编号：1761483