南京市耐多药肺结核患者的发现及纳入治疗情况分析

发布时间：2018-04-17 03:06

本文选题：耐多药肺结核 + 培养　；参考：《现代预防医学》2017年14期

【摘要】：目的分析南京市耐多药肺结核患者的发现和纳入治疗情况,为制定针对性的防治策略提供科学依据。方法2013年1月-2016年12月,对涂片阳性的慢性和复治失败、复治、初治2、3月末阳性患者及耐多药肺结核的密切接触者开展培养和药敏试验,分析不同人群中耐多药肺结核的检出情况。结果共筛查耐多药肺结核可疑者2 389例,培养阳性率64.54%。药敏试验1 383例,确诊耐多药肺结核患者144例,检出率10.41%。其中,复治失败检出率最高52.94%,各登记分类患者检出率差异有统计学意义((χ~2=29.24,P0.001)。男性耐多药检出率10.81%高于女性9.09%。青壮年、中年及60岁~组耐多药检出率较高,各年龄组检出率差异有统计学意义(χ~2=44.13,P0.001)。各区耐多药检出率在2.97%~20.61%之间,差异有统计学意义(χ~2=48.72,P0.001)。耐多药肺结核患者纳入治疗率79.86%。结论南京市耐多药肺结核检出率高于全国,患者产生与登记分类、性别、年龄及地区有关,在耐多药防治工作中应重点考虑。
[Abstract]:Objective to analyze the discovery and treatment of multidrug resistant pulmonary tuberculosis (MDR-TB) in Nanjing.Methods from January 2013 to December 2016, culture and drug sensitivity tests were carried out in chronic and relapsed smear positive patients and those who were in close contact with multidrug resistant pulmonary tuberculosis at the end of March.To analyze the detection of multidrug resistant pulmonary tuberculosis (MDR) in different populations.Results A total of 2 389 suspicious cases of MDR-TB were screened, and the positive rate of culture was 64.54%.Drug sensitivity test was performed in 1 383 cases and multidrug resistant pulmonary tuberculosis in 144 cases. The detection rate was 10.41%.Among them, the highest rate of failure was 52.94, and the difference of the detection rate among the registered and classified patients was statistically significant (蠂 ~ (2) P ~ (29. 24) P 0.001).The detection rate of multidrug resistance in male was 10.81% higher than that in female 9.09%.The detection rate of multidrug resistance was higher in young adults, middle age group and 60 years old group, and the difference was statistically significant among the different age groups (蠂 2: 44.13, P 0.001).The detection rate of multidrug resistance was between 2.97% and 20.61%, and the difference was statistically significant (蠂 2 + 48.72%, P 0.001).The treatment rate of multidrug resistant pulmonary tuberculosis patients was 79. 86%.Conclusion the detection rate of multidrug resistant pulmonary tuberculosis in Nanjing is higher than that in China. The occurrence of patients is related to the classification, sex, age and area of registration, and should be taken into account in the prevention and treatment of multidrug resistance.
【作者单位】：南京市疾病预防控制中心;
【分类号】：R521

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