新疆和田地区60岁以上维吾尔族老人肺功能与衰老相关性研究
发布时间:2018-04-18 18:51
本文选题:新疆 + 和田地区 ; 参考:《新疆医科大学》2015年硕士论文
【摘要】:目的:通过抽取新疆和田地区洛浦、墨玉、和田3个县60岁以上维吾尔族老年人行肺功能检测,分析肺功能与性别、年龄、体重、吸烟、喝酒、营养相关性,探讨影响肺功能常见危险因素,衰老与肺功能相关性,COPD导致肺功能改变的特点及新疆和田地区60岁以上维吾尔族老年人肺功能特点。方法:选取2009年4月-6月对新疆和田地区洛浦、墨玉及和田3个县农村526名完成肺功能检测的60岁以上维吾尔族老年人为研究对象,纳入280例资料完整、符合要求的研究对象,分为COPD组与正常组,同时又将两组再分为60-、71-、81-、91-四个年龄段。检测所有研究对象的一般资料,包括年龄、性别、身高、体重、吸烟、喝酒、营养状况及反应肺功能各项指标,统计被检者肺功能障碍及肺部疾病情况,分析正常组及COPD组肺功能特点及危险因素。结果:1、男性老年人肺功能各项指标均差于女性老年人,比较有统计学意义(P0.05)。2、随着年龄增长肺功能各项指标逐渐下降,比较有统计学意义(P0.05)。3、体重过低、超重、肥胖者肺功能各项指标明显低于正常体重者,比较有统计学意义(P0.05)。4、吸烟者肺功能各项指标明显低于不吸烟者,比较有统计学意义(P0.05)。5、喝酒者和不喝酒者肺功能各项指标比较无明显差异,比较无统计学意义(P0.05)。6、营养缺乏、营养过剩者肺功能各项指标低于营养适宜者,比较有统计学意义(P0.05)。7、性别、年龄、体重、营养、吸烟为影响肺功能危险因素。8、肺换气功能障者VC、RV、FRL、TLC、VE、FVC及FEF25均降低;动脉血气异常者TLC、VE、VC、FVC、FEV1/FVC值均降低;运动功能下降者RV、VE增加,VC、MVV、FVC、FEV1、FEF25各值均降低;睡眠障碍者RV、TV、TLC、VE、FVC各值均降低。9、随着年龄增长,COPD患者者及健康人肺功能各项指标均明显下降;COPD患者肺功能各项指标下降较健康人显著,比较有统计学意义(P0.05)。10、体重指数、皮下厚度为COPD患者危险因素。11、COPD患者随着年龄增加,肺功能指标逐渐降低,比较有统计学意义(P0.05)。12、随着年龄增加,健康人肺功能各指标逐渐降低,比较有统计学意义(P0.05)。13、COPD组患者肺功能各项指标明显差于非COPD者,两组比较有统计学意义(P0.05)。结论:1、男性老年人肺功能较女性老年人差;随着年龄增长肺功能逐渐下降;体重指数为影响肺功能相关因素,体重过轻、超重、肥胖者肺功能均低于体重正常者;吸烟可导致肺功能显著下降;营养缺乏、营养过剩者肺功能同样较营养正常者;喝酒对肺功能影响较小或无明显影响。2、新疆和田地区60岁以上维吾尔族老年人肺功能情况同全国肺功能标准水平相似,肺功能障碍及相关肺部疾病发生情况高于正常范围。3、肺功能障碍及肺部疾病反应出肺功能指标有部分规律性,可进一步研究通过肺功能各项异常指标对肺部功能障碍及肺疾病做出辅助诊断。4、随着年龄增长,老年患者肺功能逐渐降低,COPD患者降低程度较健康人明显,体重指数、皮下厚度可导致COPD发生率增高。
[Abstract]:Objective: to study the correlation between lung function and sex, age, body weight, smoking, drinking alcohol and nutrition in Uygur people over 60 years old in three counties of Hotan, Xinjiang.To explore the common risk factors affecting lung function, the correlation between aging and pulmonary function and the characteristics of pulmonary function changes caused by COPD and the lung function of Uygur people over 60 years old in Hotan area, Xinjiang.Methods: from April to June 2009, 526 Uygur aged over 60 years old from Luopu, Moyu and Hotan counties in Hetian area of Xinjiang were selected as the study objects. 280 cases were included in the study.The patients were divided into COPD group and normal group.The general data of all subjects, including age, sex, height, weight, smoking, alcohol consumption, nutritional status and pulmonary function, were measured.Pulmonary function and risk factors were analyzed in normal group and COPD group.Results the mean value of lung function in male was lower than that in female, and there was significant difference between male and female. With the increase of age, the indexes of lung function decreased gradually, and there was significant difference between male and female, the weight was too low, the weight was too low, and the weight was overweight.The indexes of pulmonary function in obese patients were significantly lower than those of normal body weight (P < 0.05), and the indexes of pulmonary function in smokers were significantly lower than those in non-smokers.There was no significant difference in pulmonary function indexes between drinkers and non-drinkers. There was no significant difference between the indexes of lung function between drinkers and non-drinkers, and there was no significant difference between the indexes of lung function between drinkers and non-drinkers. The indexes of pulmonary function in patients with nutritional overnourishment were lower than those with proper nutrition.Sex, age, body weight, nutrition and smoking were the risk factors of pulmonary function. The risk factors of pulmonary function were decreased in patients with pulmonary ventilation dysfunction, but decreased in patients with pulmonary ventilation dysfunction, and in patients with abnormal arterial blood gas, the values of FEV / FEV1 / FVC were decreased in patients with abnormal arterial blood gas.In the patients with motor dysfunction, the values of RVV VE increased and the values of FEV1 / FEF25 decreased, while in the patients with sleep disorders, the FVC values of RVV TVT TLCV VE decreased by 0.9, and the pulmonary function indexes of COPD patients and healthy persons decreased significantly with the age increase, and the pulmonary function indexes of COPD patients decreased more significantly than those of healthy people.There was significant difference between the two groups (P 0.05. 10, body mass index, subcutaneous thickness was the risk factor of COPD patients.) the pulmonary function index decreased with age, and the lung function index decreased gradually with the increase of age, compared with that of P0.05. 12, with the increase of age, the pulmonary function of healthy people decreased gradually.The indexes of pulmonary function in COPD group were significantly worse than those in non-COPD group, and there was significant difference between the two groups.Conclusion the lung function of male elderly is worse than that of female, and the lung function decreases gradually with the increase of age, the body mass index is the related factor of lung function, the weight is too light, overweight and obesity are lower than those with normal body weight, the lung function of male is lower than that of female.Smoking resulted in a significant decline in pulmonary function, nutrition deficiency, and nutritional overnourishment in patients with pulmonary function were also more than those with normal nutrition.Alcohol drinking had little or no obvious effect on lung function. The pulmonary function of Uygur people over 60 years old in Hotan area of Xinjiang was similar to the level of national lung function standard.The incidence of pulmonary dysfunction and related pulmonary diseases was higher than that of normal range of .3.Pulmonary dysfunction and pulmonary diseases reflected some regularity of pulmonary function.It is possible to further study the auxiliary diagnosis of pulmonary dysfunction and lung diseases by various abnormal indexes of pulmonary function. With the age, the lung function of the elderly patients gradually decreased than that of the healthy people, the degree of reduction of COPD patients was more obvious than that of the healthy people, and the body mass index (BMI) was higher in the elderly patients.Subcutaneous thickness can lead to an increased incidence of COPD.
【学位授予单位】:新疆医科大学
【学位级别】:硕士
【学位授予年份】:2015
【分类号】:R563.9
,
本文编号:1769613
本文链接:https://www.wllwen.com/yixuelunwen/huxijib/1769613.html
最近更新
教材专著