降钙素原对重症患者医院获得性肺炎的诊断价值

发布时间：2018-04-18 19:32

本文选题：降钙素原 + 医院获得性肺炎　；参考：《中华医院感染学杂志》2014年23期

【摘要】：目的研究降钙素原(PCT)对外科重症患者医院获得性肺炎的病情评估作用,为临床治疗提供参考依据。方法前瞻性纳入2011-2012年60例外科重症患者,入院后给予PCT、C-反应蛋白(CRP)等检查,根据肺炎严重程度和预后分成发生肺炎组34例与未发生肺炎组26例,分别比较重症组与轻症组PCT表达水平的差异,分析PCT与医院获得性肺炎发生的相关性,采用SPSS 12.0进行统计处理。结果纳入的60例患者中死亡8例,病死率13.33%;发生医院获得性肺炎患者共34例,发生率为56.66%;发生医院获得性肺炎的患者PCT峰值平均为(136.56±57.6)μg/L,病程中的平均值为(66.59±20.9)μg/L;未发生医院获得性肺炎的患者PCT峰值平均为(34.21±11.5)μg/L,病程中的平均值为(14.7±6.91)μg/L;两组相比,差异有统计学意义(P0.05)。结论 PCT可以有效的用于外科重症患者医院获得性肺炎的诊断,具有临床推广价值。
[Abstract]:Objective to study the effect of procalcitonin (PCT) on the evaluation of severe surgical patients with nosocomial pneumonia and to provide reference for clinical treatment.Methods from 2011 to 2012, 60 patients with severe diseases were prospectively enrolled. After admission, they were examined with PCTV-reactive protein (CRP). According to the severity and prognosis of pneumonia, they were divided into 34 cases of pneumonia group and 26 cases of non-pneumonia group.The difference of PCT expression between severe group and mild group was compared, and the correlation between PCT and nosocomial pneumonia was analyzed. SPSS 12.0 was used for statistical treatment.Results among the 60 patients included, 8 died and the mortality rate was 13.33. There were 34 patients with nosocomial pneumonia.The average peak value of PCT in patients with nosocomial pneumonia was 136.56 卤57.6 渭 g / L, and the average value of PCT in course of disease was 66.59 卤20.9 渭 g / L, while the peak value of PCT in patients without nosocomial pneumonia was 34.21 卤11.5 渭 g / L, and the average value of PCT in course of disease was 14.7 卤6.91 渭 g / L, there was significant difference between the two groups (P 0.05).Conclusion PCT can be effectively used in the diagnosis of severe surgical patients with nosocomial pneumonia.
【作者单位】：瑞安市人民医院普外科;
【基金】：瑞安市科技局基金资助项目(201203091)
【分类号】：R563.1

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