慢性阻塞性肺疾病患者并发肺结核的易感因素与临床特征分析

发布时间：2018-04-23 19:01

本文选题：慢性阻塞性肺疾病 + 肺结核　；参考：《中华医院感染学杂志》2014年04期

【摘要】：目的分析慢性阻塞性肺疾病(COPD)患者合并肺结核(TB)的易感因素,采取有针对性诊疗措施,为临床有效预防提供借鉴。方法将2010年1月-2012年12月因COPD合并TB住院治疗的107例患者为观察组,选择同期住院治疗的125例单纯性COPD患者为对照组,分析对比两组病例的临床资料,研究其发生的易感因素,所有资料录入SPSS16.0统计软件进行分析。结果两组患者主要临床特征类似,单因素χ2检验发现两组患者在年龄(χ2=4.62,P0.05)、吸烟史(χ2=6.33,P0.05)、儿时咳嗽病史(χ2=5.55,P0.05)、结核病接触史(χ2=7.27,P0.05)、粉尘接触史(χ2=4.92,P0.05)、营养不良(χ2=4.11,P0.05)以及应急事件(χ2=4.33,P0.05)等方面差异有统计学意义;对易感因素进行变量赋值后,经过logistic多因素回归分析,发现年龄(P=0.043,OR=3.815)、吸烟史(P=0.015,OR=3.495)、儿时咳嗽病史(P=0.021,OR=3.617)、结核病接触史(P=0.011,OR=3.215)、粉尘接触史(P=0.081,OR=4.587)以及应急事件(P=0.006,OR=3.085)是COPD合并TB发病的易感因素。结论影响COPD合并TB发生的因素多种多样,应根据具体情况,采取有针对性措施进行预防,以降低该类疾病的发生率。
[Abstract]:Objective to analyze the predisposing factors of pulmonary tuberculosis (TB) in patients with chronic obstructive pulmonary disease (COPD) and to provide reference for clinical effective prevention. Methods from January 2010 to December 2012, 107 patients with COPD combined with TB were selected as the observation group and 125 patients with simple COPD as the control group. The clinical data of the two groups were analyzed and compared, and the predisposing factors were studied. All data input into the SPSS16.0 statistical software for analysis. Results the main clinical features of the two groups were similar. Univariate 蠂 2 test showed that there were significant differences between the two groups in age (蠂 ~ 2 = 4.62), smoking history (蠂 ~ 2 = 6.33 / P 0.05), cough history in childhood (蠂 ~ 2 = 5.55), exposure history of tuberculosis (蠂 ~ 2 = 7.27 / P 0.05), dust exposure history (蠂 ~ 24.92 / P ~ 0.05), malnutrition (蠂 ~ 2 = 4.11 / P 0.05) and emergency events (蠂 ~ 2 = 4.33P _ 0.05). By logistic multivariate regression analysis, it was found that the age of P0. 043, the history of smoking, the history of smoking, the history of cough in childhood, the history of cough in childhood, the history of exposure to tuberculosis, the history of exposure to tuberculosis, the history of exposure to dust, the history of dust exposure, and the emergency event P0. 006 OR3.085) were the predisposing factors of COPD complicated with TB. Conclusion there are many factors affecting the occurrence of COPD complicated with TB. According to the specific situation, the prevention measures should be taken in order to reduce the incidence of this kind of disease.
【作者单位】：临安市人民医院感染性疾病科;
【基金】：浙江省临安市科技局基金资助项目(2011083)
【分类号】：R563.9

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