氨溴索静注联合雾化吸入治疗脑梗死合并肺部感染的疗效分析

发布时间：2018-05-01 00:06

本文选题：氨溴索静注 + 雾化吸入　；参考：《中华医院感染学杂志》2017年19期

【摘要】：目的探讨盐酸氨溴索静注联合雾化吸入在治疗脑梗死合并肺部感染患者中的临床疗效。方法选取医院2015年12月-2016年12月收治的脑梗死合并肺部感染患者98例,随机分为观察组和对照组,各49例,均行脑梗死及肺部感染常规治疗,对照组患者给予盐酸氨溴索注射液静脉注射,观察组在对照组基础上联合复方异丙托溴铵溶液+布地奈德雾化吸入治疗,记录并分析两组患者呼吸道症状消失时间、平均住院时间及治疗前后血气指标与肺功能检测指标。结果观察组患者治疗总有效率达到95.92%显著高于对照组79.59%(P0.05);观察组各临床表现完全消失时间及平均住院时间均显著短于对照组(P0.01);两组患者治疗前各项血气指标pH值、氧分压(PaO_2),二氧化碳分压(PaCO_2)及肺功能指标(FEV1%)比较差异无统计学意义;治疗后上述各项指标均较治疗前有明显改善(P0.05),但观察组改善情况更显著于对照组(P0.05)。结论盐酸氨溴索静注联合雾化吸入在治疗脑梗死合并肺部感染的患者中疗效较显著,显然比单纯运用盐酸氨溴索静注治疗有优势,且在一定程度上迅速缓解患者临床症状,缩短住院时间,缓解患者经济和精神压力。
[Abstract]:Objective to investigate the clinical efficacy of ambroxol hydrochloride combined with atomization inhalation in the treatment of cerebral infarction with pulmonary infection. Methods from December 2015 to December 2016, 98 patients with cerebral infarction complicated with pulmonary infection were randomly divided into observation group and control group, 49 patients in each group were treated with routine treatment of cerebral infarction and pulmonary infection. The patients in the control group were given ambroxol hydrochloride injection intravenously, the observation group was treated with budesonide atomization inhalation of compound ipratropium bromide solution on the basis of the control group, and the time for the disappearance of respiratory symptoms in the two groups was recorded and analyzed. Mean hospitalization time, blood gas and pulmonary function before and after treatment. Results the total effective rate of treatment in the observation group was 95.92%, significantly higher than that in the control group (79.59%), and the total disappearance time and average hospitalization time of each clinical manifestation in the observation group were significantly shorter than that in the control group (P 0.01), and the pH values of the blood gas indexes before treatment were significantly shorter in the observation group than in the control group. There was no significant difference in Pao _ 2, Paco _ 2 and FEV _ 1 (P _ (0.05), but the improvement in observation group was more significant than that in control group (P _ (0.05) P _ (0.05), but there was no significant difference in Pao _ (2), Paco _ (2) and FEV _ 1 (P _ (0.05), but the improvement in observation group was more significant than that in control group (P < 0.05). Conclusion Ambroxol hydrochloride combined with atomization inhalation is more effective than ambroxol hydrochloride in the treatment of cerebral infarction patients with pulmonary infection. Shorten the length of stay in hospital, ease the patient's economic and mental stress.
【作者单位】：金华市人民医院神经内科;金华市第二医院老年科;
【基金】：浙江省医药卫生科技计划基金资助项目(2013KYD276)
【分类号】：R563.1;R743.3

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