心内科住院患者肺部感染的病原菌分布及危险因素分析

发布时间：2018-05-03 16:28

本文选题：心内科 + 住院患者　；参考：《中华医院感染学杂志》2014年09期

【摘要】：目的探讨心内科住院患者肺部感染的病原菌分布及危险因素,为预防心内科住院患者肺部感染提供临床依据。方法分析医院心内科2010年6月-2012年6月1 308例住院患者肺部感染的发生率及病原学分布,调查患者的一般资料,分析心内科住院患者发生肺部感染的危险因素;采用SPSS 18.0软件进行统计分析,采用χ2检验和logistic回归模型进行危险因素的单因素分析和多因素分析。结果 1 308例患者共发生肺部感染137例,感染率为10.47%,其中上呼吸道感染61例占44.53%,下呼吸道感染76例占55.47%;共分离出病原菌137株,其中革兰阳性菌45株占32.85%;革兰阴性菌76株占55.47%;真菌16株占11.68%,排前3位的病原菌依次为金黄色葡萄球菌、铜绿假单胞菌和嗜麦芽寡养单胞菌,分别占16.06%、13.87%、11.68%;年龄、侵入性操作、机械通气、ICU停留、肺部感染史、卧床时间、血清白蛋白低及抗菌药物使用种类均为心内科住院患者肺部感染的高危因素(P0.01)。结论心内科住院患者肺部感染的发生率较高,且下呼吸道感染的比例稍高,主要病原菌为革兰阴性菌、其次为革兰阳性菌,真菌较少;该类患者发生肺部感染的危险因素较多,应针对高危因素进行预防干预。
[Abstract]:Objective to investigate the distribution and risk factors of pulmonary infection in hospitalized patients with cardiology, and to provide clinical basis for prevention of pulmonary infection. Methods the incidence and etiological distribution of pulmonary infection in 1 308 hospitalized patients from June 2010 to June 2012 were analyzed. The general data of the patients were investigated and the risk factors of pulmonary infection in hospitalized patients from June 2010 to June 2012 were analyzed. SPSS 18.0 software was used for statistical analysis, 蠂 2 test and logistic regression model were used for univariate analysis and multivariate analysis of risk factors. Results there were 137 cases of pulmonary infection in 1 308 patients, the infection rate was 10.47%, 61 cases of upper respiratory tract infection and 76 cases of lower respiratory tract infection accounted for 55.47%, 137 strains of pathogenic bacteria were isolated, among which 61 cases of upper respiratory tract infection accounted for 44.53 cases and 76 cases of lower respiratory tract infection accounted for 55.47%. Among them, 45 strains of Gram-positive bacteria accounted for 32.85; 76 strains of Gram-negative bacteria accounted for 55.47; 16 strains of fungi accounted for 11.68; the top 3 pathogens were Staphylococcus aureus, Pseudomonas aeruginosa and Maltophilia oligotrophic bacteria, accounting for 16.06% 13.87% of 11.68; Age, invasive operation, The high risk factors of pulmonary infection, history of pulmonary infection, time of bed rest, low serum albumin and use of antimicrobial agents were all high risk factors of pulmonary infection in hospitalized patients in cardiology department. Conclusion the incidence of pulmonary infection in patients with cardiology is higher, and the rate of lower respiratory tract infection is slightly higher. The main pathogenic bacteria are Gram-negative bacteria, followed by Gram-positive bacteria and less fungi, and the risk factors of pulmonary infection in these patients are more. Prevention and intervention should be carried out against high risk factors.
【作者单位】：浙江医院分院内科;浙江医院心内科;
【基金】：浙江省医药卫生科技计划基金资助项目(20140036B)
【分类号】：R563.1

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