慢支咳喘膏治疗老年支气管哮喘急性发作期患者的临床疗效

发布时间：2018-05-13 15:52

本文选题：支气管哮喘 + 慢支咳喘膏　；参考：《中国老年学杂志》2014年23期

【摘要】：目的观察慢支咳喘膏协助缓解老年支气管哮喘急性发作期轻、中度患者的临床疗效。方法同时符合西医支气管哮喘的诊断标准及分级属于轻中度急发作期并且中医属于寒哮的辨证患者共52例,肺力肺活量随机分为对照组和治疗组各26例,治疗组在与对照组相同的西药治疗基础上加服慢支咳喘膏,用药10 d后分别检测治疗组和对照组患者:症状评分、肺功能(FVC、FEV1、MVV)、嗜酸性粒细胞数(EOS)和免疫球蛋白Ig E水平。结果治疗组在加度为1.16、1.8,对照组咳嗽、胸闷分别为1.87、1.76,喘息次数和程度为3.72、3.14,治疗组与对照组比较,临床症状评分下降(P0.05)。加服慢支咳喘膏治疗后血清Ig E、EOS水平,治疗组分别为11.91±2.77、0.113±0.108,对照组为14.85±3.14、0.153±0.197,两组比较数值下降(P0.05)。肺功能FVC、FEV1、MVV指标治疗组分别为86.33±10.24、80.57±12.32、78.35±9.38,对照组分别为80.56±13.57、78.66±9.11、75.18±8.82。两组比较差异显著(P0.05)。结论慢支咳喘膏能较有效地帮助缓解老年支气管哮喘的临床症状、使肺功能指标上升,血清Ig E水平降低EOS下降。
[Abstract]:Objective to observe the clinical effect of Manzhi Kechuan ointment (MSKO) in relieving acute attack of senile bronchial asthma. Methods 52 patients with mild to moderate acute attack and cold asthma were divided randomly into two groups: control group (n = 26) and treatment group (n = 26). The treatment group was treated with Manzhi Kechuan ointment on the basis of the same western medicine as the control group. After 10 days of treatment, the patients in the treatment group and the control group were examined for symptom score, pulmonary function, FEV1MVVV, eosinophilic granulocyte count (EOS) and immunoglobulin Ig E levels. Results in the treatment group, the degrees of cough and chest tightness were 1.87 and 1.76, respectively, and the times and degree of wheezing were 3.72n3.14. The clinical symptom scores of the treatment group were decreased compared with the control group (P 0.05). The serum level of IgE EOS was 11.91 卤2.77-0.113 卤0.108 in the treatment group and 14.85 卤3.14 卤0.153 卤0.197 in the control group, respectively. The pulmonary function FVC+ FEV1 / MVV index in the treatment group was 86.33 卤10.24, 80.57 卤12.32, 78.35 卤9.38, and that in the control group was 80.56 卤13.57, 78.66 卤9.1175.18 卤8.82, respectively. The difference between the two groups was significant (P 0.05). Conclusion Manzhi Kechuan ointment can effectively relieve the clinical symptoms of bronchial asthma in the elderly, increase the pulmonary function index and decrease the level of serum IgE in patients with bronchial asthma.
【作者单位】：云南省第一人民医院干部病房;云南省第一人民医院药剂科;
【分类号】：R562.25

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