阻塞性睡眠呼吸暂停综合征患者并发缺血性脑卒中的危险因素

发布时间：2018-05-24 18:48

本文选题：阻塞性睡眠呼吸暂停综合征 + 缺血性脑卒中　；参考：《中国老年学杂志》2014年14期

【摘要】：目的探讨阻塞性睡眠呼吸暂停综合征(OSAS)患者并发缺血性脑卒中的危险因素。方法 OSAS并发缺血性脑卒中患者37例作为病例组,同时随机选取单纯OSAS患者52例作为对照组。比较两组年龄、性别比例、吸烟率、腹围、体重指数(BMI)、血脂、凝血系列、超氧化物歧化酶(SOD)水平、最长呼吸暂停时间(SAmax)、指端最低血氧饱和度(SpO2)、呼吸紊乱指数(AHI)的差别。结果两组吸烟率、腹围、BMI、血脂、凝血系列、SOD水平、SAmax、指端最低SpO2、AHI均有显著性差别(P0.05)。多因素logistic回归分析结果显示,BMI、SAmax、指端最低SpO2、AHI具有统计学意义(P0.05),其比值比分别是2.709(95%CI为1.185~6.191)、2.055(95%CI为1.053~4.009)、1.982(95%CI为1.091~3.063)、2.091(95%CI为1.047~4.178)。结论 BMI、SAmax、SpO2、AH是OSAS并发缺血性脑卒中的危险因素。OSAS患者脑卒中的发生与其肥胖程度及疾病的严重程度有关。
[Abstract]:Objective to investigate the risk factors of ischemic apoplexy in patients with obstructive sleep apnea syndrome (OSAS). Methods 37 patients with ischemic stroke were used as case group, and 52 cases of simple OSAS patients were randomly selected as control group. The age, sex ratio, smoking rate, abdominal circumference, body mass index (BMI), blood lipid and coagulation were compared between the two groups. Series, the level of superoxide dismutase (SOD), the longest apnea time (SAmax), the lowest blood oxygen saturation (SpO2) and the respiratory disorder index (AHI) at the fingertip. Results two groups of smoking rates, abdominal circumference, BMI, blood lipid, blood clotting series, SOD level, SAmax, the lowest SpO2 in the fingertip, and AHI (P0.05). The results of multiple factor Logistic regression analysis showed that BMI, SAmax, the lowest SpO2, AHI has statistical significance (P0.05), and the ratio ratio is 2.709 (95%CI 1.185~6.191), 2.055 (95%CI is 1.053~4.009), 1.982 (95%CI is 1.091~3.063), 2.091 (95%CI for). The extent of the disease is related to the severity of the disease.
【作者单位】：中国医科大学附属盛京医院第二呼吸内科;
【分类号】：R56

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