血必净对重症肺炎患者的疗效分析

发布时间：2018-06-05 10:09

本文选题：血必净 + 重症肺炎患者　；参考：《中国生化药物杂志》2014年05期

【摘要】：目的考察血必净注射液对重症肺炎患者的治疗作用。方法选择100例医院重症肺炎患者平均随机分为对照组和治疗组(n=50),对照组给予营养支持、机械通气等基础治疗,治疗组在此基础上给予血必净治疗。流式细胞术检测对照组和治疗组治疗前及治疗后的CD4+、CD8+、NK水平、以及酶联免疫吸附法检测白介素-1(IL-1)、IL-6、肿瘤坏死因子-α(TNF-α)。结果相比于对照组,治疗组治疗的患者总有效率高于对照组,有显著性差异(P0.05);治疗组治疗后IL-1、IL-6、TNF-α水平相比于治疗前和对照组都有明显降低,有显著性差异(P0.05);与对照组和治疗组治疗前相比较,治疗组治疗后的CD4+/CD8+比值、NK水平都有显著性提高(P0.05)。结论血必净对于基础治疗后的重症肺炎患者病情有明显改善作用,具有显著的治疗效果。
[Abstract]:Objective to investigate the therapeutic effect of Xuebijing injection on patients with severe pneumonia. Methods 100 patients with severe pneumonia in hospital were randomly divided into two groups: control group and treatment group. The control group was given nutritional support, mechanical ventilation and other basic treatment, and the treatment group was treated with Xuebijing on this basis. Flow cytometry was used to detect the NK level of CD4 and CD8 in control group and treatment group before and after treatment, and the levels of IL-6, TNF- 伪 and TNF- 伪 were detected by enzyme-linked immunosorbent assay (Elisa). Results compared with the control group, the total effective rate of the patients in the treatment group was higher than that in the control group (P 0.05), and the level of IL-6 TNF- 伪 in the treatment group was significantly lower than that before treatment and in the control group. Compared with the control group and the treatment group, the CD4 / CD8 ratio and NK level in the treatment group were significantly higher than those in the control group and the treatment group. Conclusion Xuebijing can obviously improve the condition of patients with severe pneumonia after basic treatment.
【作者单位】：海南省人民医院重症医学科;重庆医科大学附属第一医院呼吸科;
【基金】：国家自然科学基金(c030306)
【分类号】：R563.1

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