BiPAP在急性呼吸窘迫综合征治疗中的应用

发布时间：2018-06-06 10:39

本文选题：双水平气道正压通气 + 急性呼吸窘迫综合征　；参考：《山东医药》2015年23期

【摘要】：目的观察双水平气道正压通气(Bi PAP)在急性呼吸窘迫综合征(ARDS)治疗中的应用效果。方法86例ARDS患者随机分为观察组和对照组各43例,两组患者均给予控制感染、氧疗、早期使用皮质激素等常规对症治疗,观察组在此基础上采用Bi PAP行经鼻(面)罩正压机械通气治疗。观察两组治疗前后动脉血气、血流动力学、肺功能变化。结果与同组治疗前比较,观察组治疗后2 h血氧分压(Pa O2)、血氧饱合度(Sa O2)水平及治疗后12 h p H、Pa O2、Sa O2水平升高(P均0.05),对照组治疗后12 h Pa O2、Sa O2水平升高(P均0.05);与对照组比较,观察组治疗后12 h p H、Pa O2、Sa O2水平升高(P均0.05)。与同组治疗前比较,观察组治疗后3 h中心静脉压、心指数水平降低(P均0.05)。与治疗前比较,观察组治疗后2周FVC%、FEV1%增加,对照组治疗后2周FVC%增加(P均0.05);与对照组比较,观察组治疗后2周FVC%、FEV1%增加(P均0.05)。结论 Bi PAP在ARDS治疗中的应用效果显著,其可有效纠正低氧血症,减少CO2潴留,改善氧合与肺功能,且对血流动力学无负面影响。
[Abstract]:Objective to observe the effect of BiPAP in the treatment of acute respiratory distress syndrome (ARDS). Methods 86 patients with ARDS were randomly divided into observation group (n = 43) and control group (n = 43). The observation group was treated with BiPAP through nasal (facial) mask positive pressure mechanical ventilation. The changes of arterial blood gas, hemodynamics and pulmonary function were observed before and after treatment. Results compared with the same group before treatment, the blood oxygen partial pressure (Pao _ 2), the degree of blood oxygen saturation (sa _ O _ 2) and the level of Pa _ (2) O _ (2) sa _ (O _ 2) increased in the observation group at 2 h after treatment, and the level of Pa _ (2) O _ (2) sa _ (2) O _ (2) increased at 12 h after treatment in the control group (P < 0.05), and compared with that in the control group (P < 0.05). In the observation group, the levels of Pa O 2 O 2 and sa O 2 increased at 12 h after treatment (P < 0.05). Compared with the same group before treatment, the central venous pressure and cardiac index decreased at 3 h after treatment in the observation group (P < 0.05). Compared with before treatment, FEV 1% increased 2 weeks after treatment in the observation group, 0.05% increased in the control group 2 weeks after treatment, and 0.05% increased in the observation group 2 weeks after treatment, and the FEV 1% increased 0.05% in the observation group 2 weeks after treatment. Conclusion BiPAP is effective in the treatment of ARDS. It can effectively correct hypoxemia, reduce CO _ 2 retention, improve oxygenation and pulmonary function, and has no negative effect on hemodynamics.
【作者单位】：上海中医药大学附属曙光医院;
【分类号】：R563.8

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