阿奇霉素与左氧氟沙星治疗社区获得性下呼吸道感染疗效对比观察

发布时间：2018-06-07 14:03

本文选题：阿奇霉素 + 左氧氟沙星　；参考：《中华医院感染学杂志》2016年16期

【摘要】：目的研究社区获得性下呼吸道感染患者采用阿奇霉素及左氧氟沙星治疗的临床效果,为社区获得性下呼吸道感染临床治疗提供理论依据。方法选择2013年5月-2015年5月诊治的176例急性社区获得性下呼吸道感染患者,将其均分为对照组88例采用左氧氟沙星治疗,观察组88例采用阿奇霉素治疗,比较两组患者的临床治疗效果,数据采用SPSS 15.0软件进行统计分析。结果观察组患者有效率为95.5%、对照组为81.8%,观察组患者的总有效率高于对照组;观察组患者退热、咳嗽、咳痰、肺部哮鸣音消失时间明显比对照组快;观察组患者不良反应发生率为6.8%、对照组为20.5%,;两组比较差异均有统计学意义(P0.05)。结论急性社区获得性下呼吸道感染患者采用阿奇霉素治疗临床效果显著,安全性高,不良反应少,值得临床推广应用。
[Abstract]:Objective to study the clinical effects of azithromycin and levofloxacin in the patients with community acquired lower respiratory tract infection, and to provide a theoretical basis for the clinical treatment of community acquired lower respiratory tract infection. Methods 176 patients with acute community-acquired lower respiratory tract infection were selected in May -2015 in May 2013, and the patients were divided into 88 of the control group. Cases were treated with levofloxacin. 88 cases in the observation group were treated with azithromycin, and the clinical therapeutic effects of two groups were compared. The data were analyzed by SPSS 15 software. The results showed that the effective rate of the observation group was 95.5% and the control group was 81.8%. The total effective rate of the observation group was higher than that of the control group; the patients in the observation group were fever, cough, expectoration, lung. The disappearance time of the buzzing sound was faster than the control group, the incidence of adverse reactions in the observation group was 6.8% and the control group was 20.5%, and the difference between the two groups was statistically significant (P0.05). Conclusion azithromycin treatment in the patients with acute community-acquired lower respiratory tract infection was significant, high safety, and less adverse reactions, worthy of clinical promotion. Application.
【作者单位】：中国医科大学航空总医院呼吸科;南昌大学第二附属医院呼吸科;
【基金】：北京市自然科学基金资助项目(8052021)
【分类号】：R56

【相似文献】