中国澳门地区健康成人脉冲振荡肺功能测定及预计值方程式探讨

发布时间：2018-06-11 21:48

本文选题：脉冲振荡肺功能 + 气道阻力　；参考：《中国实用内科杂志》2015年05期

【摘要】：目的探讨中国澳门地区健康成人脉冲振荡(impulse oscillometry system,IOS)肺功能特点,建立适合中国澳门地区健康成人的IOS预计值方程式。方法随机选取2011—2012年无吸烟史的中国澳门地区中国籍健康成人362例。采用德国Jaeger公司的Master Screen脉冲振荡肺功能测定仪进行检测,指标包括潮气量(VT)、呼吸总阻抗(Z5),5 Hz及20 Hz时呼吸阻力(R5、R20)和呼吸电抗(X5、X20);响应频率(RF)等,将所得的实测值分别与年龄(A,岁)、身高(H,cm)、体重(W,kg)、相对体重(CW)及性别行相关分析,同时进行多元逐步线性回归分析,得出预计值方程式;并与其他预计值方程式进行对比。结果上述气道阻力指标在各年龄组间差异无统计学意义;男女不同性别组间有统计学意义;气道阻力各主要指标预计值方程式分别为:男:Z5=1.380-0.007×H+0.002×W;R5=1.346+0.002×W-0.007×H;R20=0.972-0.004×H;X5=-0.434+0.002×H;X20=-0.037-0.0004×A+0.001×H;RF=25.81+0.033×A-0.099×H。女:Z5=0.802+0.002×A-0.004×H+0.122×CW;R5=0.227+0.001×A+0.308×CW-0.003×W;R20=0.8 7 5-0.0 0 3×H;X 5=-0.4 2 3+0.0 0 2×H+0.0 0 0 1×A;X 2 0=0.1 6 6+0.0 0 0 1×A-0.0 4 4×C W;RF=3.69+0.086×A+9.493×CW-0.08×W。结论建立了适合中国澳门地区人群的IOS各主要指标的预计值方程式,建议推广应用。
[Abstract]:Objective to study the characteristics of pulmonary function of healthy adults in Macao, China, and to establish an iOS prediction equation suitable for healthy adults in Macao, China. Methods 362 healthy Chinese adults with no smoking history from 2011 to 2012 were randomly selected. Using Master screen Pulsed Oscillation Pulsed Pulmonary function Measurement instrument of Jaeger Company of Germany, the indexes include tidal volume, total respiratory impedance, respiratory resistance at 5 Hz and 20 Hz, and respiratory reactance X 5 X 20; response frequency, RF), etc. The measured values were correlated with age, height, weight, relative weight and sex, respectively. At the same time, multivariate stepwise linear regression analysis was carried out to get the predicted value equation, and to compare it with other predicted value equations. Results there was no significant difference in airway resistance between different age groups, there was statistical significance between male and female groups, and the predicted value equations of the main parameters of airway resistance were as follows: male: Z5V 1.380-0.007 脳 H 0.002 脳 W 0.002 R51.346 0.002 脳 W-0.007 脳 HHX R2070.972-0.004 脳 HX57-0.434 0.002 脳 HX2037-0.0004 脳 A 0.001 脳 HRRF25.81 0.033 脳 A-0.099 脳 H. Female: Z5: 0. 802 0.002 脳 A-0.004 脳 H 0.122 脳 CWV R5U 0.227 0.001 脳 A 0.308 脳 CW-0.003 脳 WW R20 0. 8 7 5-0.003 脳 Hu X 5G -0.4 23 002 脳 H 0.001 脳 H 0.001 脳 AX 20 0 0 0.1 66 0001 脳 A-0.044 脳 C WFV 3.69 0.086 脳 A 9.493 脳 CW-0.08 脳 W. Conclusion the predicted value equations of iOS are established for the population of Macao, China, and it is suggested that they should be popularized and applied.
【作者单位】：中国澳门镜湖医院呼吸内科;广州医科大学附属第一医院广州呼吸疾病研究所呼吸疾病国家重点实验室国家呼吸疾病临床研究中心;中国澳门镜湖医院健康中心;
【基金】：中国澳门科技基金(014/2010/A)
【分类号】：R56

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