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降钙素原监测在老年患者治疗呼吸机相关性肺炎中的作用

发布时间:2018-07-13 12:53
【摘要】:目的探讨血清降钙素原(PCT)监测对接受门诊治疗的老年呼吸机相关性肺炎(VAP)患者使用的抗生素指导意义。方法选择接受门诊治疗的老年VAP患者59例,根据随机对照原则分为PCT组29例,常规治疗组30例。入组患者均监测血清PCT水平,在进行常规治疗的同时,常规治疗组根据我国VAP治疗指南选择抗生素治疗方案;PCT组在血清PCT≥0.25μg/L时使用抗生素治疗,PCT0.25μg/L时不予抗生素治疗,复诊时亦按照此标准决定是否继续使用抗生素。观察上述两组的相关临床指标及抗生素使用率。结果 PCT组治疗后血清PCT水平低于治疗前。PCT监测组的抗生素使用率低于常规治疗组,两组患者的预后无明显差异(P0.05)。结论门诊接受治疗的VAP患者可以依据PCT水平指导抗生素应用,能够减少抗生素使用率,缩短抗生素疗程,降低抗生素费用。
[Abstract]:Objective to investigate the significance of serum procalcitonin (PCT) monitoring in the use of antibiotics in elderly patients with ventilator-associated pneumonia (VAP). Methods 59 elderly VAP patients received outpatient treatment were randomly divided into PCT group (29 cases) and routine treatment group (30 cases). Serum PCT levels were monitored in all patients. While routine therapy was carried out, the routine treatment group selected antibiotics according to our country's VAP treatment guidelines. The PCT group did not receive antibiotic treatment when the serum PCT was 鈮,

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