呼吸机相关性气管支气管炎对机械通气患者临床预后的影响

发布时间：2018-08-01 16:17

【摘要】：目的:分析呼吸机相关性气管支气管炎对机械通气患者临床预后的影响。方法:对四会市人民医院2015年10月至2017年2月收治的88例呼吸机相关性气管支气管炎患者予以分组研究,根据是否继发呼吸机相关性肺炎(VAP)分为两组,即对照组(n=53)、VAP组(n=35),对两组患者治疗时抗生素使用情况及治疗后机械通气时间与住院时间予以统计比较。结果:VAP组患者混合感染率为31.4%,多重耐药菌分离率为82.9%,均高于对照组患者的13.2%、50.9%,组间比较,差异具有统计学意义(P0.05)。VAP组患者抗生素合理使用率为45.7%,低于对照组患者的92.5%,组间比较,差异具有统计学意义(P0.05)。VAP组患者机械通气时间为(13.5±3.8)d,住院时间为(16.9±5.1)d,均长于对照组患者的(9.3±3.6)d、(11.3±5.2)d,组间比较,差异具有统计学意义(P0.05)。结论:在机械通气中,早期给予合理抗生素治疗,可有效控制呼吸机相关性气管支气管炎的进展,对预防VAP有着积极的意义。
[Abstract]:Objective: to analyze the effect of ventilator associated bronchitis on the prognosis of patients with mechanical ventilation. Methods: 88 patients with ventilator-associated bronchitis treated in Sihui people's Hospital from October 2015 to February 2017 were divided into two groups according to whether they had secondary ventilator-associated pneumonia (VAP). The patients in the control group (n / 53) and VAP group (n / 35) were treated with antibiotics and the time of mechanical ventilation and hospitalization were compared statistically. Results the mixed infection rate and multidrug resistant bacteria isolation rate in the VAP group were 31.4 and 82.9, respectively, which were higher than those in the control group. The difference was statistically significant (P0.05). The rational use rate of antibiotics in the VAP group was 45.7, which was lower than that in the control group (92.5%). The difference was statistically significant (P0.05). The time of mechanical ventilation was (13.5 卤3.8) days, the hospitalization time was (16.9 卤5.1) days, which was longer than that of the control group (9.3 卤3.6) d, (11.3 卤5.2 days). The difference was statistically significant (P0.05). Conclusion: early treatment with antibiotics in mechanical ventilation can effectively control the progress of ventilator-associated tracheal bronchitis and has positive significance for the prevention of VAP.
【作者单位】：四会市人民医院;
【分类号】：R563.1

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