布地奈德联合复方异丙托溴铵雾化吸入治疗超高龄慢性阻塞性肺疾病急性加重患者的临床疗效

发布时间：2018-08-11 18:09

【摘要】：目的:探讨布地奈德(普米克令舒)联合复方异丙托溴铵(可必特)雾化吸入治疗超高龄慢性阻塞性肺疾病急性加重(AECOPD)患者的临床疗效。方法:60例患者随机分为治疗组和对照组各30例,治疗组给予普米克令舒和可必特加入一次性雾化器中,氧驱动雾化吸入每日2次,每次20-30min,连续治疗7d。对照组给予α-糜蛋白酶加庆大霉素加生理盐水10ml氧驱动雾化吸入治疗,每日2次,每次20-30min,连续治疗7d。两组同时给予抗炎、吸氧和平喘等常规治疗。观察各组患者总有效率,治疗前后临床症状的改善情况、住院时间、血气分析指标及不良反应。结果:治疗组总有效率、临床症状改善、血气分析结果、住院时间与对照组比较有显著差别(P0.01),不良反应极少。结论:普米克令舒联合可必特雾化吸入治疗AECOPD患者有显著疗效,且方便、简单、安全值得推广使用。
[Abstract]:Objective: to investigate the clinical effect of budesonide (PMT) combined with compound ipratropium bromide (CPB) atomization inhalation in the treatment of (AECOPD) patients with acute exacerbation of chronic obstructive pulmonary disease (COPD). Methods Sixty patients were randomly divided into treatment group (n = 30) and control group (n = 30). In the treatment group, Pulmicort and Corbide were added into a disposable atomizer. Oxygen driven atomization inhalation was administered twice a day for 20-30 min for 7 days. The control group was treated with 伪 -chymotrypsin plus gentamicin plus saline 10ml oxygen-driven atomization inhalation twice daily for 20-30 min for 7 days. Both groups were given routine treatment such as anti-inflammatory, oxygen inhalation and anti-asthmatic therapy at the same time. The total effective rate, the improvement of clinical symptoms, hospital stay, blood gas analysis and adverse reactions were observed. Results: the total effective rate, clinical symptom improvement, blood gas analysis and hospitalization time in the treatment group were significantly different from those in the control group (P0.01). Conclusion: Pulmicort lotion combined with Kapidil atomization inhalation is effective in the treatment of AECOPD patients. It is convenient, simple, safe and worth popularizing.
【作者单位】：广州军区武汉总医院干部病房一科;
【分类号】：R563.9

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