慢性充血性心力衰竭并发肺功能损伤的相关危险因素及生存分析

发布时间：2018-08-28 10:09

【摘要】：目的探讨慢性充血性心力衰竭并发肺功能损伤的相关危险因素及生存分析。方法选取2009年1月至2011年12月该院诊断为慢性充血性心力衰竭并行肺功能检查的患者327例,依据第1秒用力呼气量(FVC)预计值将其分为3组:A组(肺功能正常,FVC预计值大于70%),B组(轻度肺功能损伤,FVC预计值60%~70%),C组(中-重度肺功能损伤,FVC预计值小于60%),随访至2013年1月,随访内容包括患者的基线资料及预后情况,通过Logistic回归分析慢性充血性心力衰竭并发中-重度肺功能损伤的相关危险因素,Cox回归分析慢性充血性心力衰竭全因死亡的危险因素,Kaplan-Meier生存曲线分析比较不同严重程度肺功能损伤的生存率。结果 (1)慢性充血性心力衰竭并发肺功能损伤的患者有167例(51.1%),其中,并发中-重度肺功能损伤的为96例(29.4%);体质量指数(BMI)、吸烟、增大的心胸比为慢性充血性心力衰竭并发中-重度肺功能损伤的独立相关危险因素(P0.05);(2)心功能Ⅲ~Ⅳ级、中-重度肺功能损伤是慢性充血性心力衰竭全因死亡的独立危险因素(P0.05);(3)C组与A组、C组与B组之间生存率比较差异有统计学意义(P0.05),A、B组间差异无统计学意义(P0.05)。结论并发肺功能损伤在慢性充血性心力衰竭的患者中比较常见,且中-重度的肺功能损伤严重影响患者的预后。
[Abstract]:Objective to investigate the risk factors and survival of chronic congestive heart failure complicated with lung function injury. Methods from January 2009 to December 2011, 327 patients with chronic congestive heart failure and pulmonary function examination were selected. According to the forced expiratory volume (FVC) predicted value in the first second, the patients were divided into three groups: group A (normal lung function > 70%) and group C (60% with mild lung function injury) and group C (with moderate to severe lung function injury < 60%). The patients were followed up until January 2013. The follow-up included baseline data and prognosis. Kaplan-Meier survival curve analysis of chronic congestive heart failure with Logistic regression analysis of risk factors associated with moderate to severe lung function injury Survival rate of severe lung injury. Results (1) there were 167 cases (51.1%) of chronic congestive heart failure complicated with lung function injury, 96 cases (29.4%) of them were complicated with moderate to severe lung function injury, and the body mass index (BMI),) smoked. The increased cardiothoracic ratio was an independent risk factor for moderate to severe lung function injury in chronic congestive heart failure (P0.05); (2). Moderate to severe lung function injury was an independent risk factor for all death of chronic congestive heart failure (P0.05); (3). There was significant difference in survival rate between C group and A group C group and B group (P0.05). Conclusion Pulmonary function injury is more common in patients with chronic congestive heart failure, and moderate to severe lung function injury seriously affects the prognosis of patients with chronic congestive heart failure.
【作者单位】：重庆市万州区人民医院心内科;
【分类号】：R541.6;R563.8

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