127例耐多药肺结核CT影像学改变与临床

发布时间：2018-10-10 17:40

【摘要】：目的探讨耐多药肺结核的影像学特点,提高对耐多药肺结核的认识。方法收集本院诊治的耐多药肺结核患127例为观察组,同期药物敏感肺结核患者130例为对照组。全部患者均做胸部CT扫描。对病变范围、病变形态及治疗后病变变化情况进行分析。结果观察组(102例)病变分布广泛,累及3个肺叶以上及全肺受侵69例,明显多于对照组,二者比较差异有统计学意义(P0.05)。在病变形态上观察组肺内实变(73例)、广泛播散灶(85例)、多发空洞(56例)、胸膜增厚(73例)、合并毁损(37例)及支扩(58例)等方面明显多于对照组,差异有统计学意义(P0.05)。观察组(47例)病变进展多于对照组(6例),观察组(36例)好转病例少于对照组(95例),差异有统计学意义(P0.05)。结论耐多药肺结核肺内病灶分布广泛,形态多样,多发播散、多发空洞及并发症多,常表现为重症肺结核,治疗效果不佳。
[Abstract]:Objective to investigate the imaging features of multi-drug resistant pulmonary tuberculosis (MDR) and to improve the understanding of MDR TB. Methods 127 cases of multidrug resistant pulmonary tuberculosis treated in our hospital were collected as observation group and 130 cases of drug sensitive pulmonary tuberculosis as control group. All patients underwent chest CT scan. The range, morphology and changes of pathological changes after treatment were analyzed. Results the pathological changes were widely distributed in the observation group (102 cases), involving more than 3 lobes and the whole lung in 69 cases, which was obviously more than that in the control group. The difference between the two groups was statistically significant (P0.05). The number of pulmonary consolidation (73 cases), diffuse foci (85 cases), multiple cavity (56 cases), pleural thickening (73 cases), combined lesion (37 cases) and branch dilatation (58 cases) in the observation group was significantly higher than that in the control group (P0.05). The progress of disease in observation group (47 cases) was more than that in control group (6 cases), while in observation group (36 cases) it was less than that in control group (95 cases), the difference was statistically significant (P0.05). Conclusion Multi-drug resistant pulmonary tuberculosis is characterized by extensive distribution of pulmonary lesions, diverse morphology, multiple spread, multiple cavity and multiple complications, which is often characterized by severe pulmonary tuberculosis with poor therapeutic effect.
【作者单位】：重庆市公共卫生医疗救治中心放射科;重庆市公共卫生医疗救治中心科教科;
【分类号】：R521;R816.41

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