肺动脉栓塞的危险分级与多项指标的临床相关性应用

发布时间：2018-11-17 15:55

【摘要】：目的评估血浆D二聚体(DD)等血凝标志物、心肌损伤标志物、血气分析等在肺动脉栓塞(PE)危险分层诊断及预后的临床价值。方法 201例PE患者其中高危组52例,中危组88例,低危组61例,治疗组67例,正常对照组38例。分析多项指标的表达水平。结果 PE者高危组、中危组和低危组的DD、纤维蛋白原(Fib)、N末端脑钠肽(NT-pro BNP)水平、凝血酶原时间(PT)、氧分压(PO_2)与治疗组和或正常对照组比较差异具有统计学意义(P0.05),而除低危组外,高危组与中危组的肌钙蛋白I(cTnⅠ)、肌酸激酶同工酶(CK-MB)、国际标准化比值(INR)、凝血酶原活动度(PTA)和呼吸指数(RI)比较差异具有统计学意义(P0.05),二氧化碳分压(PCO_2)仅中危组差异具有统计学意义(P0.05),但肌酸激酶(CK)和血氧饱和度(SpO_2)差异无统计学意义(P0.05)。结论联合多项指标不仅可作为肺动脉栓塞的危险分层鉴别诊断指标,其浓度的变化有助于判断预后及指导治疗。
[Abstract]:Objective to evaluate the clinical value of plasma D-dimer (DD), myocardial injury marker and blood gas analysis in the risk stratification diagnosis and prognosis of pulmonary embolism (PE). Methods there were 52 cases in high risk group, 88 cases in middle risk group, 61 cases in low risk group, 67 cases in treatment group and 38 cases in normal control group. The expression level of multiple indexes was analyzed. Results the levels of DD, fibrinogen (Fib), N terminal brain natriuretic peptide (NT-pro BNP) and prothrombin time (PT),) in high risk group, middle risk group and low risk group in PE patients were analyzed. The difference of oxygen partial pressure (PO_2) between the treatment group and the control group was statistically significant (P0.05), but the cardiac troponin I (cTn 鈪，

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