血清降钙素原及C-反应蛋白对老年下呼吸道感染患者病情与预后评估中的作用

发布时间：2019-03-17 16:28

【摘要】：目的分析血清降钙素原(PCT)和C-反应蛋白(CRP)检测在老年人下呼吸道感染病情和预后评估中的作用,为合理治疗提供客观依据。方法选取2013年12月-2014年12月100例老年下呼吸道感染患者作为病例组,选取100名健康老年人作为对照组,对两组研究对象血清PCT和CRP水平进行检测和比较,对于病例组患者的呼吸衰竭发生率进行观察和记录;采用SPSS17.0软件进行统计分析。结果病例组患者的血清PCT和CRP水平均显著高于对照组,差异均有统计学意义(t=17.483、25.044,P0.05);随着病情严重程度的加剧,患者的血清PCT和CRP水平呈现逐步上升,差异均有统计学意义(P0.05);发生呼吸衰竭患者的血清PCT和CRP水平显著高于未发生呼吸衰竭,差异均有统计学意义(t=8.793、18.414,P0.05)。结论老年下呼吸道感染患者表现为血清PCT和CRP水平均升高,其水平与患者的病情严重程度和预后具有相关性,可作为早期诊断、病情评估和预后预测的辅助指标。
[Abstract]:Aim to analyze the role of serum procalcitonin (PCT) and C-reactive protein (CRP) in the assessment of the condition and prognosis of lower respiratory tract infection in the elderly, so as to provide objective evidence for rational treatment. Methods from December 2013 to December 2014, 100 elderly patients with lower respiratory tract infection were selected as case group and 100 healthy elderly as control group. Serum PCT and CRP levels were measured and compared between the two groups. The incidence of respiratory failure in the case group was observed and recorded. SPSS17.0 software was used for statistical analysis. Results the levels of serum PCT and CRP in the case group were significantly higher than those in the control group (t = 17.483, 25.044, P0.05). With the severity of the disease, the level of serum PCT and CRP gradually increased, the difference was statistically significant (P0.05); The levels of serum PCT and CRP in patients with respiratory failure were significantly higher than those without respiratory failure (t = 8.793, 18.414, P0.05). Conclusion the serum levels of PCT and CRP in elderly patients with lower respiratory tract infection are both elevated, which are correlated with the severity and prognosis of the patients. It can be used as a supplementary index for early diagnosis, assessment and prognosis prediction of the patients with lower respiratory tract infection.
【作者单位】：武汉市普爱医院体检中心;武汉市普爱医院泌尿外科;
【基金】：湖北省科技厅基金资助项目(EK2013D160056001525)
【分类号】：R56

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