气管插管持续湿化对预防肺部感染的效果分析

发布时间：2019-03-21 19:57

【摘要】：目的研究可湿化气管插管持续湿化气道对降低痰液黏稠度、避免反复吸痰导致气道黏膜损伤及预防肺部感染的效果,为临床治疗提供参考依据。方法调查2011年1月-2013年2月共387例行气管插管的患者临床资料,选择2011年1-12月219例患者随机分为两组,对照1组92例患者采用普通气管插管,试验1组127例患者采用可湿化气管插管,选择同样0.45%氯化钠湿化液;选择2012年9月-2013年2月168例,将其随机分为试验2组、对照2组,各84例,观察各组患者肺部感染的发生率。结果试验1组患者湿化合格93例、合格率73.23%,对照1组患者湿化合格22例、合格率23.91%,两组患者合格率比较差异有统计学意义(P0.01);试验2组患者肺部感染发生率为22.62%,明显低于对照组的54.76%,差异有统计学意义(P0.05)。结论用可湿化气管插管的专用湿化通道持续湿化,避免了频繁吸痰对气道黏膜损伤引起的感染、避免了痰液蓄积滋生细菌生长,对维持气道黏膜自净功能及预防肺部感染效果显著。
[Abstract]:Objective to study the effect of continuous humidification of airway by humidifying tracheal intubation on reducing sputum viscosity, avoiding repeated sputum aspiration and preventing lung infection, so as to provide reference for clinical treatment. Methods the clinical data of 387 patients undergoing endotracheal intubation from January 2011 to February 2013 were investigated. 219 patients from January to December 2011 were randomly divided into two groups: control group (n = 92) and control group (n = 92). In group 1, 127 patients were treated with humidifiable tracheal intubation and the same 0.45% sodium chloride humidifying solution was selected. 168 cases from September 2012 to February 2013 were randomly divided into trial group 2 (n = 84) and control group 2 (n = 84). The incidence of pulmonary infection in each group was observed. Results 93 cases (73.23%) were qualified for humidification in trial group 1, and 22 cases (23.91%) were qualified for humidification in control group 1. There was significant difference between the two groups (P0.01). The incidence of pulmonary infection in test 2 group was 22.62%, which was significantly lower than that in control group (54.76%) (P0.05). Conclusion it can avoid the infection caused by frequent sputum suction and avoid the growth of bacteria in sputum accumulation by using the special humidification channel for humidifying trachea intubation, which can avoid the infection caused by frequent inhalation of sputum to airway mucosa injury, and prevent the growth of bacteria in sputum accumulation. It has significant effect on maintaining airway mucosa self-purification function and preventing pulmonary infection.
【作者单位】：江西省信丰县人民医院ICU;
【基金】：江西省重点基金资助项目(20122CX17900)
【分类号】：R563.1

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