AIDS与非AIDS患者肺毛霉菌病影像表现对比分析研究

发布时间：2019-03-22 12:13

【摘要】：目的探讨AIDS患者与非AIDS患者肺毛霉菌病影像表现的特点，并对比分析两组患者胸部影像表现异同点，，为临床诊断奠定影像学基础。材料与方法搜集经真菌培养确诊肺毛霉菌病患者33例，全部病例均行胸部X线平片和/或CT检查。本研究患者分成两组：AIDS组（24例）和非AIDS组（9例），分别总结分析两组患者影像表现并分析，影像观察内容包括：肺内病灶部位、数量、形态、大小、密度、边界；纵隔淋巴结情况；两侧腋窝淋巴结情况；高分辨率CT肺间质表现。结果肺毛霉菌病的常见征象有肺纹理增粗、肺内斑片状渗出性病灶、双肺多发粟粒样结节影、磨玻璃样密度影、肺气囊、纵隔淋巴结肿大、胸腔积液等。其中肺内多发渗出性病灶发生于非AIDS组（9例，100%）的概率高于AIDS组（14例，58.3%），两组差异具有统计学意义（p=0.032）；双肺多发粟粒样结节影则更多见于AIDS组（9例37.5%）,非AIDS组未见（0例），两组差异具有统计学意义(P=0.039）结论肺毛霉菌病的影像表现可多种多样；肺毛霉菌病在非AIDS组以肺部渗出性改变明显；在AIDS组则以双肺多发粟粒样结节影为特点。
[Abstract]:Objective to investigate the imaging features of pulmonary mycosis in AIDS patients and non-AIDS patients, and to compare and analyze the similarities and differences of chest imaging manifestations between the two groups, so as to lay the imaging basis for clinical diagnosis. Materials and methods 33 cases of pulmonary mycosis diagnosed by fungal culture were collected. All cases were examined by chest X-ray and / or CT. The patients in this study were divided into two groups: AIDS group (24 cases) and non-AIDS group (9 cases). The imaging findings of the two groups were summarized and analyzed, including the location, number, shape, size, density and boundary of the lesions in the lung. Mediastinal lymph nodes; bilateral axillary lymph nodes; High-resolution CT pulmonary interstitial manifestations. Results the common signs of pulmonary mycosis included thickening of lung texture, patch-like exudative lesions in the lungs, miliary nodules in both lungs, ground glass density shadows, pulmonary airbags, enlargement of mediastinal lymph nodes, pleural effusion, and so on. The incidence of multiple exudative lesions occurred in non-AIDS group (9 cases, 100%) was higher than that in AIDS group (14 cases, 58.3%), and there was significant difference between the two groups (p < 0.032). Multiple miliary nodular shadows in both lungs were more common in AIDS group (9 cases 37.5%) than non-AIDS group (0 cases). Conclusion the imaging manifestations of pulmonary mycosis can be varied. Pulmonary mycosis was characterized by pulmonary exudation in the non-AIDS group and multiple miliary nodular shadows in both lungs in the AIDS group.
【学位授予单位】：广州医学院
【学位级别】：硕士
【学位授予年份】：2012
【分类号】：R512.91;R519

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