临床肠内营养支持对老年慢性阻塞性肺病患者心肺功能影响的干预研究

发布时间：2019-06-30 21:26

【摘要】：目的探讨肠内营养对老年慢性阻塞性肺病(chronic obstructive pulmonary disease,COPD)患者心肺功能的影响。方法选择老年COPD稳定期患者58例,常规治疗基础上随机分为2组,其中治疗组29例(肠内营养),对照组29例(自由饮食)。治疗前后检测各项营养指标(血清总蛋白、白蛋白、前白蛋白)、LVEF、肺功能[第一秒用力呼气容积(FEV1),用力肺活量(FVC)]。结果治疗组治疗后体质量指数、血清总蛋白、白蛋白、前白蛋白水平较治疗前明显升高,而对照组以上各项指标改善不明显。治疗组治疗后体质量指数、血清总蛋白、白蛋白、前白蛋白水平较对照组明显改善,差异有统计学意义(P0.05)。治疗组治疗后LVEF[(48.98±6.38)%vs(42.38±5.98)%,(42.73±5.34)%]、FVC[(2.98±0.38)Lvs(2.75±0.31)L,(2.76±0.34)L]、FEV1[(2.06±0.87)Lvs(1.78±0.72)L,(1.92±0.90)L]、FEV1/FVC[(78.36±12.32)vs(70.65±12.28),(71.23±12.55)]较治疗前和对照组明显改善,差异有统计学意义(P0.05)。结论老年COPD患者,在常规治疗的同时给予肠内营养治疗,可以改善患者营养状况,进一步改善患者心肺功能,缩短住院时间。
[Abstract]:Objective to investigate the effect of enteral nutrition on cardiopulmonary function in elderly patients with chronic obstructive pulmonary disease (chronic obstructive pulmonary disease,COPD). Methods 58 elderly patients with stable COPD were randomly divided into two groups on the basis of routine treatment, including 29 patients in the treatment group (enteral nutrition) and 29 patients in the control group (free diet). The nutritional indexes (serum total protein, albumin, prealbumin), LVEF, pulmonary function [forced breath volume (FEV1) in the first second, forced vital capacity (FVC)] were measured before and after treatment. Results after treatment, the levels of body mass index, serum total protein, albumin and prealbumin in the treatment group were significantly higher than those before treatment, but the above indexes in the control group were not significantly improved. After treatment, the body mass index, serum total protein, albumin and prealbumin levels in the treatment group were significantly higher than those in the control group (P 0.05). In the treatment group, LVEF [(48.98 卤6.38)% vs (42.38 卤5.98)%, (42.73 卤5.34)%], FVC [(2.98 卤0.38) Lvs (2.75 卤0.31) L, (2.76 卤0.34) L], FEV1 [(2.06 卤0.87) Lvs (1.78 卤0.72) L, (1.92 卤0.90) L], FEV1/FVC [(78.36 卤12.32) vs (70.65) L] (71.23 卤12.55)] was significantly improved compared with the control group before treatment, the difference was statistically significant (P 0.05). Conclusion the treatment of enteral nutrition in elderly patients with COPD can improve the nutritional status of the patients, further improve the cardiopulmonary function of the patients, and shorten the hospitalization time.
【作者单位】：湖州市第三人民医院老年病科;
【分类号】：R563.9

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