血清白细胞介素-10评估不同年龄免疫功能受损并重症肺炎患者病情严重程度及预后的价值

发布时间：2019-07-21 10:02

【摘要】：目的探讨血清白细胞介素(IL)-10评估不同年龄免疫功能受损并重症肺炎患者病情严重程度及预后的价值。方法 180例免疫功能受损并重症肺炎患者,根据年龄分为非老年组(年龄60岁,112例)、老年组(年龄≥60岁,68例);入院后行APACHEⅡ评分、淋巴细胞亚群及血清IL-10水平检测;比较两组患者病情严重程度及结局差异,血清IL-10表达水平差异及与病情严重程度的关系。结果相比于非老年组,老年组病情重,APACHEⅡ评分较高[非老年组(24.22±7.51)分,老年组(36.53±13.52)分],死亡率高(非老年组51.79%,老年组73.53%;P0.05);老年患者血清IL-10水平[(6.72±1.97)mg/dl]低于非老年组[(9.66±2.58)mg/dl,P0.05];相关性分析显示,血清IL-10水平与APACHEⅡ评分呈负相关。结论检测免疫受损合并重症肺炎患者血清IL-10水平,有助于评估及预测病情严重程度及预后。
[Abstract]:Objective to evaluate the value of serum IL-10 in evaluating the severity and prognosis of patients with severe pneumonia with immune impairment in different ages. Methods according to age, 180 patients with severe pneumonia were divided into non-elderly group (age 60 years, 112 cases) and elderly group (age 鈮，

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